CAS N/A MFCD00011796-甲硫酸新斯的明甲硫酸新斯的明 TAO{mole}

甲硫酸新斯的明甲硫酸新斯的明

CAS N/A MFCD00011796

化学结构图

SMILES:

化学属性

Mol. Formula	C13H22N2O6S
Mol. Weight	334.39
Melting Point	145.0 to 149.0 deg-C
Solubility	1G/10ML
Density	1.0
Boiling Point	107℃

别名和识别编码

Chemical Name	Neostigmine methyl sulfate
Synonym	Ammonium, (3-(dimethylcarbamoyloxy)phenyl)trimethyl-, methylsulfate N,N,N-三甲基-2-[(二甲氨基)甲酰氧基]苯铵甲磺酸盐 AR-32 Ammonium, (m-hydroxyphenyl)trimethyl-, methyl sulfate, dimethylcarbamate Carbamic acid, N,N-dimethyl-, 3-dimethylaminophenyl ester, methosulfate (3-Dimethylcarbamoyloxyphenyl)trimethylammonium Methyl Sulfate
MDL Number	MFCD00011796
CAS Number	51-60-5
EC Number	200-109-5
PubChem Substance ID	87573782
Reaxys-RN	3848275
Merck Number	6464
Chemical Name Translation	甲硫酸新斯的明
Beilstein Registry Number	3848275
Wiswesser Line Notation	1N1&VOR CK1&1&1 &Q &OSW1
LabNetwork Molecule ID	LN00195311
InChI	InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

分类

{SNA} Acetylcholinesterase, Analytical and Industrial Enzymes, Bioactive Small Molecule Alphabetical Index, Cholinesterase Inhibitors, Cholinesterase and Organophosphate Detection Reagents, Enzyme Inh
{SNA} Analytical Standards, EP Standards, EP Standards N - O, Pharmacopeia & Metrological Institutes Standards, 分析/色谱
{SNA} Acetylcholinesterase, Analytical and Industrial Enzymes, Bioactive Small Molecule Alphabetical Index, Biochemicals and Reagents, Cholinesterase Inhibitors, Cholinesterase and Organophosphate Detection Reagents, Enzyme Inhibitors, N, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, 生物活性小分子, 细胞信号转

产品应用

校准仪器和装置；评价方法；工作标准；质量保证/质量控制；其他

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P301+P310
P301+P310+P330
P305+P351+P338
P305+P351+P338+P337+P313
P332+P313
P337+P313
P342+P311
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H300 Fatal if swallowed 吞食致命
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSCY1225000

Signal word

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes T+

Safety Statements

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R28 Very toxic if swallowed 吞咽极毒
R42/43

Packing GroupII

UN Number 2811

Hazard Class6.1

Storage condition 储存温度 -20°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 310 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 81,276,1950

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 99,16,1950

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Tec

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1400 ug/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - sex ratio
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 8,1986,1974