10,11-Dihydro-5H-Dibenzo[B,F]Azepine-5-Carbonyl Chloride 10,11-二氢-5H-二苯并[b,f]氮杂卓-5-甲酰氯

CAS 33948-19-5 MFCD00012314

化学结构图

33948-19-5
SMILES: O=C(Cl)N1C2=CC=CC=C2CCC2C=CC=CC1=2

化学属性

Mol. FormulaC15H12ClNO
Mol. Weight257.72
Melting Point120.0 to 124.0 deg-C

别名和识别编码

Chemical Name10,11-Dihydro-5H-Dibenzo[B,F]Azepine-5-Carbonyl Chloride
CAS Number33948-19-5
Synonym 亚氨基二苄甲酰氯 酰氯亚氨基二苄 5-Chlorocarbonyl-10,11-dihydro-5H-dibenz[b,f]azepine 5-(Chlorocarbonyl)-10,11-dihydrodibenzazepine 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carbonyl Chloride
MDL NumberMFCD00012314
PubChem Substance ID87559742
EC Number251-756-5
Reaxys-RN196970
Beilstein Registry Number20(3/4)3905
Chemical Name Translation10,11-二氢-5H-二苯并[b,f]氮杂卓-5-甲酰氯
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Others
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, N-Containing, Other Heterocyclic Building Blocks
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics

产品应用

  • Carbamazepine intermediate.

相关文献及参考

  • Duart, M., et al.: J. Med. Chem., 48, 1260 (2005),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P303+P361+P353+P310+P363
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P304+P340+P310
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P405 Store locked up. 上锁保管。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P304+P340
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P305+P351+P338+P310
  • P301+P330+P331+P310
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Hazard Codes C
Risk Statements
  • R34 Causes burns 会导致灼伤
UN Number 3261
Packing GroupII
Hazard Class8

系列性分类


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