2-(Diethylamino)Ethyl 2-Hydroxy-2,2-Diphenylacetate Hydrochloride 2-(二乙氨基)乙基-2-羟基-2,2-二苯基乙酸酯盐酸盐
CAS 57-37-4 MFCD00012624
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} Building Blocks, C12 to C63, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
产品应用
- Benactyzine is an antagonist of acetylcholine in the central and peripheral nervous system. Benactyzine is used as an antispasmodic.
相关文献及参考
- Fournier, P., et al.: Therapie, 17, 1245 (1962),
- Kosmachev, A., et al.: J. Neurochem., 71, 21 (1998),
- Mayorga, J., et al.: Brain Res., 829, 180 (1999),
安全信息
GHS Symbol

- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P310+P330
- P302+P352
- P304+P340
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
- P330 Rinse mouth. 漱口
- P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H301 Toxic if swallowed 吞食有毒
- H311 Toxic in contact with skin 皮肤接触中毒
- H331 Toxic if inhaled 吸入中毒
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg/kg TOXIC EFFECTS
TYPE OF TEST : LD50 -
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 15 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,363,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - excitement Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 11,405,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 14300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JCAE "Prehl
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC,
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 500 ug/kg SEX/DURATION : male 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles) REFERENCE : PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 10,44,1966
其他信息
- 储运特性:通风低温干燥; 与库房食品原料分开存放
- TCI Shanghai:盐酸贝那替嗪 Benactyzine Hydrochloride,>;98.0%(T)(57-37-4)
- 方法一:由二苯乙醇酸与1-氯-2二乙氨基乙烷反应得到。将甲苯、二苯乙醇酸和1-氯-2-二乙氨基乙烷在反应锅内加热回流3h,冷却结晶,甩滤得到的粗品经精制即为该品。
- 上游原料:乙胺 --> 二苯基乙醇酸
- 毒性分级:高毒
- 用途一:抗胆碱药。
- 图谱信息:乙胺痉平 (57-37-4)红外图谱(IR1) 乙胺痉平 (57-37-4)红外图谱(IR2) 乙胺痉平 (57-37-4)核磁图( 13 CNMR) 乙胺痉平 (57-37-4)核磁图( 1 HNMR) 乙胺痉平 (57-37-4)质谱(MS) 乙胺痉平 (57-37-4)Raman光谱
- 急性毒性:口服-大鼠 LD50; 184 毫克/公斤; 口服-小鼠 LD50: 160 毫克/公斤
- MOL 文件:57-37-4.mol
- 可燃性危险特性:燃烧产生有毒氮氧化物和氯化氢烟雾;极少量服用则精神失常
- Sigma Aldrich:57-37-4(sigmaaldrich)
- 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
- 类别:有毒物品