CAS 553-24-2 MFCD00012651-Neutral Red 中性红 TAO{mole}

Neutral Red 中性红

CAS 553-24-2 MFCD00012651

化学结构图

SMILES: Cl.CC1=CC2=NC3=CC=C(C=C3N=C2C=C1N)N(C)C

化学属性

Mol. Formula	C15H17ClN4
Mol. Weight	288.78
Melting Point	290
Solubility	50 G/L
Density	1.422
Stability	对湿度敏感

别名和识别编码

Chemical Name	Neutral Red
Synonym	3-氨基-6-二甲氨基-2-甲基吩嗪盐酸盐 3-氨基-7-二甲基氨基-2-甲基吩嗪盐酸盐 3-氨基-7-二甲基氨基-2-甲基吩嗪盐酸盐中性红溶液二苯乙烯红 3-氨基-7-二甲基氨基-2-甲基吩嗪盐酸盐二苯乙烯红 Basic Red 5 C.I. Basic Red 5 C.I. Basic Red 5, monohydrochloride Cerven neutralni Cerven toluylenova Cerven zasadita 5 Neutral Red W Neutral red,IND {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {hazard_com} Toluylene Red 中性红溶液中性红溶液 (0.33%) 二苯乙烯红
MDL Number	MFCD00012651
CAS Number	553-24-2
EC Number	209-035-8
Reaxys-RN	3918740
Beilstein Registry Number	3918740
PubChem Substance ID	87573672
Merck Number	6488
Chemical Name Translation	中性红
Wiswesser Line Notation	T C666 BN INJ E1 FZ LN1&1 &GH
LabNetwork Molecule ID	LN00193691
Canonical SMILES	NC1=CC2=NC3=CC(N(C)C)=CC=C3N=C2C=C1C.[H]Cl

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产品应用

酸碱指示剂，生物染色剂。pH 6.8(红)-8.0(黄)。水、亚硝酸盐和尿的碱度指示剂。组织化学中用于脂肪的水解指示剂。神经细胞的尼尔(Nissl)小粒染色。与健那绿共用于血液体外活体染色。碘离子的光度测定。中性红试纸的制备。

安全信息

WGK Germany3

Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSSG1400000

Hazard Codes Xn

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险

Signal word Warning

GHS Symbol

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

Storage condition 2-8°C, protect from light 密封保存。

{hazard_

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 112 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 10,337,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 142 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   E

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 96600 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   SMBUA9 Stanford Medical Bulletin.  (Palo Alto, CA)  V.1-20, 1942-62.
   Discontinued.  Volume(issue)/page/year: 9,96,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 432 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China
   International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24-
   1989-  Volume(issue)/page/year: 25,356,1990

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm
REFERENCE :
   AMNTA4 American Naturalist.  (Univ. of Chicago Press, Journals Div., POB
   37005, Chicago, IL 60637) V.1-    1867-  Volume(issue)/page/year:
   87,295,1953

TYPE OF TEST            : Mutation in

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 93,185,1982

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Bird - chicken
DOSE/DURATION           : 85 ug/kg
REFERENCE :
   47JMAE "Cytogenetic Assays of Environmental Mutagens,"  Hsu, T.C., ed.,
   Totowa, NJ, Allanheld, Osmun & Co., 1982  Volume(issue)/page/year:
   -,137,1982

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Fish - not otherwise specified
DOSE/DURATION           : 1 ppm/4D (Continuous)
REFERENCE :
   MUREAV Mutation Resear

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2500 ppt/3H
REFERENCE :
   AMNTA4 American Naturalist.  (Univ. of Chicago Press, Journals Div., POB
   37005, Chicago, IL 60637) V.1-    1867-

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 2 umol/L/5H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 45,233,1977

TYPE OF TEST

其他信息

溶于水溶液呈红色；溶于醇，溶液呈黄色并微带荧光。溶解度为水4.0%，无水乙醇1.8%，乙二醇乙醚3.75%，乙二醇3.0%。几乎不溶于二甲苯，其水溶液或乙醇溶液呈红色。最大吸收波长(50%乙醇)553nm。半数致死量(大鼠，静脉)112mg/kg。
溶解度为水4.0%，无水乙醇1.8%，乙二醇乙醚3.75%，乙二醇3.0%。几乎不溶于二甲苯，其水溶液或乙醇溶液呈红色。最大吸收波长(50%乙醇)553nm。半数致死量(大鼠，静脉)112mg/kg。