CAS 23491-45-4 MFCD00012679-4-(5-(4-Methylpiperazin-1-Yl)-1H,1'H-[2,5'-Bibenzo[D]Imidazol]-2'-Yl)Phenol Trihydrochloride 4-(5-[5-(4-甲基-1-哌嗪基)-2H-苯并咪唑-2-亚基]-5H-苯并咪唑-2-基)苯酚三盐酸盐 TAO{mole}

4-(5-(4-Methylpiperazin-1-Yl)-1H,1'H-[2,5'-Bibenzo[D]Imidazol]-2'-Yl)Phenol Trihydrochloride 4-(5-[5-(4-甲基-1-哌嗪基)-2H-苯并咪唑-2-亚基]-5H-苯并咪唑-2-基)苯酚三盐酸盐

CAS 23491-45-4 MFCD00012679

化学结构图

SMILES: Cl.Cl.Cl.CN1CCN(CC1)C1=CC2N=C(NC=2C=C1)C1=CC2N=C(NC=2C=C1)C1C=CC(O)=CC=1

化学属性

Mol. Formula	C25H27Cl3N6O
Mol. Weight	534
Melting Point	314 ºC
Solubility	可溶

别名和识别编码

Chemical Name	4-(5-(4-Methylpiperazin-1-Yl)-1H,1'H-[2,5'-Bibenzo[D]Imidazol]-2'-Yl)Phenol Trihydrochloride
Synonym	Hoechst Dye 33258 Bisbenzimide Hoechst 33258 HOE 33058 NSC334072 甲嗪双苯咪酚三盐酸盐 H 33258 赫斯特荧光染料 33258 溶液 BXI-72 Hoechst 33258 溶液烟酸己可碱三盐酸盐 Bisbenzimidazole trihydrochloride Bisbenzimide H 33258 NSC-322921 赫斯特荧光染料 33258 33258 Hoechst BBIH Phenol, 4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)-, Hoechst Stain solution Bisbenzimide; p-(5-(5-(4-Methyl-1-piperazinyl)-1H-2-benzimidazolyl)-1H-2-benzimidazolyl)phenol trihydrochloride BBIH BXI-72 HOE 33258 Hoechst 33258 NSC334072 烟酸己可碱三盐酸盐甲嗪双苯咪酚三盐酸盐 HOE 33258
CAS Number	23491-45-4
PubChem Substance ID	172089156
EC Number	245-690-6
Beilstein Registry Number	4088183
MDL Number	MFCD00012679
Chemical Name Translation	4-(5-[5-(4-甲基-1-哌嗪基)-2H-苯并咪唑-2-亚基]-5H-苯并咪唑-2-基)苯酚三盐酸盐
Reaxys-RN	4088183
Wiswesser Line Notation	T56 BM DNJ CR DQ& G- CT56 BM DNJ G- AT6N DNTJ D1 &GH3

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

GHS Symbol

WGK Germany3

Hazard Codes Xn

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H302 Harmful if swallowed 吞食有害
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

RTECSSM1140500

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P302+P352+P332+P313+P362+P364
P332+P313
P305+P351+P338
P305+P351+P338+P337+P313
P302+P350
P337+P313

Signal word Warning

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；

Risk Statements

R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
R22 Harmful if swallowed 吞咽有害

Storage condition <0°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36900 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB84-171206

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 32200 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB84-171206

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 1600 nmol/L
REFERENCE :
   CHROAU Chromosoma.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1939-  Volume(issue)/page/year:
   52,297,1975

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - rat Fibroblast
DOSE/DURATION           : 1 mg/L
REFERENCE :
   ZZACAG Zeitschrift fuer Zellforschung und Mikroskopische Anatomie. (Berlin,
   Fed. Rep. Ger.) V.1-147, 1924-73.  For publisher information, see CTSRCS. 
   Volume(issue)/page/year: 104,127,1970

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 2 umol/L
REFERENCE :
   CHROAU Chromosoma.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1939-  Volume(issue)/page/year:
   52,297,1975

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Fibroblast
DOSE/DURATION           : 1 mg/L
REFERENCE :
   ZZACAG Zeitschrift fuer Zellforschung und Mikroskopische Anatomie. (Berlin,
   Fed. Rep. Ger.) V.1-147, 1924-73.  For publisher information, see CTSRCS. 
   Volume(issue)/page/year: 104,127,1970

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 umol/L
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 258,121

4-(5-(4-Methylpiperazin-1-Yl)-1H,1'H-[2,5'-Bibenzo[D]Imidazol]-2'-Yl)Phenol Trihydrochloride 4-(5-[5-(4-甲基-1-哌嗪基)-2H-苯并咪唑-2-亚基]-5H-苯并咪唑-2-基)苯酚三盐酸盐

CAS 23491-45-4 MFCD00012679

化学结构图

化学属性

别名和识别编码

分类

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