3-(3-Chloro-4-Methylphenyl)-1,1-Dimethylurea 3-(3-氯-4-甲基苯基)-1,1-二甲基脲

CAS 15545-48-9 MFCD00018275

化学结构图

15545-48-9
SMILES: CC1C=CC(=CC=1Cl)NC(=O)N(C)C

化学属性

Mol. FormulaC10H13ClN2O
Mol. Weight212.70

别名和识别编码

Chemical Name3-(3-Chloro-4-Methylphenyl)-1,1-Dimethylurea
CAS Number15545-48-9
Synonym 3-(3-Chloro-4-methylphenyl)-1,1-dimethyl-urea 绿麦隆 Dicuran Highuron Clortokem C 2242 Tolurex Chlorotoluron ######## 3-(3-Chloro-p-tolyl)-1,1-dimethylurea; N'-(3-Chloro-4-methylphenyl)-N,N-dimethylurea; N-(3-Chloro-4-methylphenyl)-N',N'-dimethylurea Chlortoluron N-(3-Chloro-4-methylphenyl)-N',N'-dimethylurea 3-(3-Chlor-4-methylphenyl)-1,1-dimethylharnstoff
MDL NumberMFCD00018275
Beilstein Registry Number2647688
EC Number239-592-2
PubChem Substance ID24868874
Chemical Name Translation3-(3-氯-4-甲基苯基)-1,1-二甲基脲
Wiswesser Line NotationGR B1 EMVN1&1
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分类

  • Alphabetic, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography, Environmental Standards, Herbicides, Pesticides & Metabolites, Urea structure
  • {SA} Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography, Environmental Standards, Pesticides & Metabolites
  • {SNA} Alphabetical Index of Analytical Standards, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, C, CH, Chromatography,

产品应用

  • Herbicide.

相关文献及参考

  • Nelieu, S., et al.: Environ. Toxicol. Chem., 29, 2644 (2010),
  • Merck 14 ,2172

安全信息

Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H351 Suspected of causing cancer 怀疑致癌
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
RTECSYS7230000
GHS Symbol
WGK Germany3
Hazard Codes Xn;N Xn,N
Precautionary statements
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Warning
Safety Statements
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R50/53
UN Number 3077
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHZDAN Khigiena i Zdraveopazvane.  Hygiene and Sanitation.  (Hemus, Blvd.
   Russki 6, Sofia, Bulgaria) V.9-    1966-  Volume(issue)/page/year:
   22,362,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,161,1991

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1300 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,353,1978

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,353,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 mg/kg
SEX/DURATION            : male 50 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(11),78,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2 gm/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   KHZDAN Khigiena i Zdraveopazvane.  Hygiene and Sanitation.  (Hemus, Blvd.
   Russki 6, Sofia, Bulgaria) V.9-    1966-  Volume(issue)/page/year:
   22,362,1979

系列性分类


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