Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester 2-羟基苯甲酸-2-羧基苯基酯
CAS 552-94-3 MFCD00020252
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资金保障
专业采购外包团队在线服务
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分类
- {SNA} Arachidonic Acid Cascade, Bioactive Small Molecules, Cell Signaling and Neuroscience, Cyclooxygenase, Enzyme Inhibitors, Lipids in Cell Signaling, S, 细胞生物学
- {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Cyclooxygenase, Enzyme Inhibitors, Lipids in Cell Signali
产品应用
- Usually used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.
相关文献及参考
- [2]. Scheiman JM, et al. Gastroduodenal mucosal damage with salsalate versus aspirin: results of experimental models and endoscopic studies in humans. Semin Arthritis Rheum. 1990;20(2):121-127.
- [3]. González F, et al. Salicylate administration suppresses the inflammatory response to nutrients and improves ovarian function in polycystic ovary syndrome. Am J Physiol Endocrinol Metab. 2020;319(4):E744-E752.
- Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),
- Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980),
- [1]. Murthy SN, et al. Effects of salsalate therapy on recovery from vascular injury in female Zucker fatty rats. Diabetes. 2010;59(12):3240-3246.
- [1]. Murthy SN, et al. Effects of salsalate therapy on recovery from vascular injury in female Zucker fatty rats. Diabetes. 2010;59(12):3240-3246.
- [2]. Scheiman JM, et al. Gastroduodenal mucosal damage with salsalate versus aspirin: results of experimental models and endos
安全信息
GHS Symbol


- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S37 Wear suitable gloves 戴适当手套;
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
- R22 Harmful if swallowed 吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R50 Very toxic to aquatic organisms 对水生生物极毒
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312+P330
- P302+P352
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- H302 Harmful if swallowed 吞食有害
- H315 Causes skin irritation 会刺激皮肤
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1020 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 22,1101,1980
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 2229 mg/kg/2Y-I TOXIC EFFECTS : Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) REFERENCE : AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 107,116,1987
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 665 mg/kg SEX/DURATION : female 17 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Effects on Embryo or Fetus - other effects to embryo Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 29,250,1971
其他信息
- 用途:用作止痛消炎药
- 双水杨酸酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 S0129 水杨酸2-羧基苯酯 2-Carboxyphenyl Salicylate 500G 1320元 2014/06/02 S0129 水杨酸2-羧基苯酯 2-Carboxyphenyl Salicylate 25G 306元 2010/06/21 133400250 双水杨酸酯 Salicylsalicylic acid 99% 25 GR 729元
- EPA化学物质信息:Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester(552-94-3)
- MOL 文件:552-94-3.mol
- RTECS号:DH2080000
- Salsalate
- NIST化学物质信息:2-Carboxyphenyl salicylate(552-94-3)