N-Hydroxysulfosuccinimide sodium salt N-羟基琥珀酰亚胺磺酸钠盐
CAS 106627-54-7 MFCD00043100
化学结构图
SMILES: ON1C(=O)CC(C1=O)S(O)(=O)=O
化学属性
| Mol. Formula | C4H4NNaO6S |
|---|---|
| Mol. Weight | 217 |
| Melting Point | 250 |
| TSCA | No |
| Density | 0.995 |
| Boiling Point | 82 °C |
| Solubility | Soluble in Methanol and Water |
| Stability | 对湿度和热敏感 |
别名和识别编码
| Chemical Name | N-Hydroxysulfosuccinimide sodium salt |
|---|---|
| CAS Number | 106627-54-7 |
| Alfabeta Name | HYDROXYSULFOSUCCINIMIDESODIUMSALT N- |
| MDL Number | MFCD00043100 |
| Synonym | |
| PubChem Substance ID | 125307542 |
| Beilstein Registry Number | 6359129 |
| Reaxys-RN | 6359129 |
| Chemical Name Translation | N-羟基琥珀酰亚胺磺酸钠盐 |
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分类
- {SNA} Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling, Synthetic Reagents
产品应用
- 多肽缩合剂，可形成稳定的活泼酯中间体。用于制备亲水性活泼酯，比如作为蛋白交联剂。
安全信息
- H315 Causes skin irritation 会刺激皮肤
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
GHS Symbol
其他信息
- N-Hydroxysulfosuccinimide Sodium Salt is a variant of N-Hydroxysuccinimide, derivatized with a sulfate group to confer hydrophilicity. N-Hydroxysulfosuccinimide Sodium Salt can be utilized similarly to NHS to activate carboxylic acids of interest to the more reactive succinimidyl esters for coupling, biotinylation, and conjugation with fluorophores. Also used for crosslinking agents.
- 溶解度: 0.3 g/l水 (20 C) 易溶于乙醇、乙醚、氯仿和乙酸乙酯。
