MYXOTHIAZOL
CAS 76706-55-3 MFCD00043397
化学结构图
SMILES: CC(C)/C=C/C=C/[C@H](C)C1=NC(=CS1)C1=NC(=CS1)/C=C/[C@H](OC)[C@@H](C)/C(=C/C(N)=O)/OC
化学属性
| Mol. Formula | C25H33N3O3S2 |
|---|---|
| Mol. Weight | 487.73 |
别名和识别编码
| Chemical Name | 2,6-Heptadienamide,7-(2'-(1,6-dimethyl-2,4-heptadienyl)(2,4'-bithiazol)-4-yl)-3,5-dimethoxy- 4-methyl- |
|---|---|
| MDL Number | MFCD00043397 |
| PubChem Substance ID | 24897044 |
| Synonym | Myxothiazol |
| CAS Number | 76706-55-3 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Bioactive Small Molecules, Cell Biology, Chemical Structure Class, Inhibits an Enzyme, M, Mechanism of Action, Peptides, Spectrum of Activity
相关文献及参考
- [2]. von Jagow G,et al. An inhibitor of mitochondrial respiration which binds to cytochrome b and displaces quinone from the iron-sulfur protein of the cytochrome bc1 complex. J Biol Chem. 1984;259(10):6318-6326.
- [3]. Davoudi M, et al. A mouse model of mitochondrial complex III dysfunction induced by myxothiazol. Biochem Biophys Res Commun. 2014;446(4):1079-1084.
- [1]. Thierbach G, et al. Myxothiazol, a new antibiotic interfering with respiration. Antimicrob Agents Chemother. 1981;19(4):504-507.
- [1]. Thierbach G, et al. Myxothiazol, a new antibiotic interfering with respiration. Antimicrob Agents Chemother. 1981;19(4):504-507.
- [2]. von Jagow G,et al. An inhibitor of mitochondrial respiration which binds to cytochrome b and displaces quinone from the iron-sulfur protein of the cytochrome bc1 complex. J Biol Chem. 1984;259(10):6318-6326.
- [3]. Davoudi M, et al. A mouse model of mitochondrial complex III dysfunction induced by myxothiazol.
安全信息
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P310
- H300 Fatal if swallowed 吞食致命
GHS Symbol
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,1474,1980
