TetraisopropylpyrophosphamideTetraisopropyl Tetraisopropyl

CAS 513-00-8 MFCD00048272

化学结构图

513-00-8
SMILES: CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C

化学属性

Mol. FormulaC12H32N4O3P2
Mol. Weight342.36

别名和识别编码

Chemical NameTetraisopropylpyrophosphamideTetraisopropyl
Synonym Iso OMPA Iso-OMPA Tetra(monoisopropyl)pyrophosphortetramide Tetra(monoisopropyl)pyrophosphortetramide iso-OMPA Tetraisopropyl pyrophosphoramide Tetraisopropylpyrophosphamide iso-OMPA
MDL NumberMFCD00048272
PubChem Substance ID5420
CAS Number513-00-8
EC Number208-149-5
Chemical Name TranslationTetraisopropyl
InChIKeyIOIMDJXKIMCMIG-UHFFFAOYSA-N
InChIInChI=1S/C12H32N4O3P2/c1-9(2)13-20(17,14-10(3)4)19-21(18,15-11(5)6)16-12(7)8/h9-12H,1-8H3,(H2,13,14,17)(H2,15,16,18)
LabNetwork Molecule IDLN04679281
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分类

  • {SNA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cholinesterase, butyryl, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, T
  • {SNA} A to C, Cholinesterase, butyryl, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,

相关文献及参考

  • Koelle, G.B., et al. Biochem. Pharmacol. 23 , 175, (1974) 摘要
  • Wang, Y., et al., Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase. Toxicol. Appl. Pharmacol. 196 , 356-66, (2004) 摘要
  • Sklan, E.H., et al., Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study Proc. Natl. Acad. Sci. U. S. A. 101 , 5512-7, (2004) 摘要
  • Mabe, A.M., and Hoover, D.B., Structural and functional cardiac cholinergic deficits in adult neurturin knockout mice Cardiovasc. Res. 82 , 93-9, (2009) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P304+P340+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P403+P233
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Signal word Danger
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H312 Harmful in contact with skin 皮肤接触有害
  • H301 Toxic if swallowed 吞食有毒
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
Hazard Codes T+
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S22 Do not breathe dust 不要吸入粉尘;
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒

系列性分类


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