CAS 543-38-4 MFCD00055781-L-Canavanine L-刀豆氨酸 TAO{mole}

L-Canavanine L-刀豆氨酸

CAS 543-38-4 MFCD00055781

化学结构图

SMILES: NC(N)=NOCCC(N)C(=O)O

化学属性

Mol. Formula	C5H12N4O3
Mol. Weight	176

别名和识别编码

Chemical Name	L-Canavanine
MDL Number	MFCD00055781
CAS Number	543-38-4
Synonym	Canavanin L-Canavanine Canavanine L-刀豆氨酸 L-Homoserine, O-((aminoiminomethyl)amino)- L-α-Amino-γ-(guanidinooxy)-n-butyric acid O-((Aminoiminomethyl)amino)-L-homoserine L-α-Amino-γ-(guanidinooxy)-n-butyric acid
PubChem Substance ID	439202
Chemical Name Translation	L-刀豆氨酸
Wiswesser Line Notation	QVYZ2OMYZUM
InChI	InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1

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安全信息

WGK Germany3

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Hazard statements

H332 Harmful if inhaled 吸入有害
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害

RTECSES7002000

Signal word Warning

GHS Symbol

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；

Hazard Codes Xn

Risk Statements

R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 8(1),100,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5900 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   91,395,1987

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7 gm/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   91,395,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 12,349,1971

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION           : 2200 umol/L
REFERENCE :
   JCLLAX Journal of Cellular Physiology.  (Alan R. Liss, Inc., 41 E. 11th St.,
   New York, NY 10003) V.67-    1966-  Volume(issue)/page/year: 75,129,1970