CAS 31842-01-0 MFCD00057144-2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoic acid 2-(4-(1-氧代异吲哚啉-2-基)苯基)丙酸 TAO{mole}

2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoic acid 2-(4-(1-氧代异吲哚啉-2-基)苯基)丙酸

CAS 31842-01-0 MFCD00057144

化学结构图

SMILES: CC(C(O)=O)C1C=CC(=CC=1)N1CC2C=CC=CC=2C1=O

化学属性

Mol. Formula	C17H15NO3
Mol. Weight	281

别名和识别编码

Chemical Name	2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoic acid
CAS Number	31842-01-0
Synonym	Indoprofen Propionic acid, alpha-(4-(1-oxo-2-isoindolinyl)phenyl)- Flosin Reumofene 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone K 4277 Propionic acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)- 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-alpha-methylbenzeneacetic acid 吲哚洛芬 Isindone alpha-(4-(1-Oxo-2-iso-indolinyl)-phenyl)-propionic acid ######## Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-methyl- 1-Oxo-2-(p-((alpha-methyl)carboxymethyl)phenyl)isoindoline Flosint α-Methyl-p-(1-oxo-2-isoindolinyl)benzeneacetic acid p-(1-Oxo-2-isoindolinyl)-hydratropic acid
MDL Number	MFCD00057144
PubChem Substance ID	24896022
EC Number	250-833-0
Chemical Name Translation	2-(4-(1-氧代异吲哚啉-2-基)苯基)丙酸
Wiswesser Line Notation	T56 BVN DHJ CR DY1&VQ

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

A non-steroidal anti-inflammatory agent

安全信息

RTECSMU6645000

GHS Symbol

Precautionary statements

P301+P310
P281 Use personal protective equipment as required. 使用所需的个人防护装备。

Hazard statements

H351 Suspected of causing cancer 怀疑致癌
H301 Toxic if swallowed 吞食有毒

WGK Germany3

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S22 Do not breathe dust 不要吸入粉尘；

Hazard Codes T

Risk Statements

R25 Toxic if swallowed 吞咽有毒
R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1100,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 84 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1100,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 84 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   112,291,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 36,1037,1981