Bestatin hydrochloride 乌苯美司盐酸盐
CAS 65391-42-6 MFCD00058004
化学结构图
SMILES: Cl.CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(O)=O
化学属性
| Mol. Formula | C16H24N2O4·HCl |
|---|---|
| Mol. Weight | 344.84 |
| Melting Point | 216-218° |
| TSCA | No |
别名和识别编码
| Chemical Name | Bestatin hydrochloride |
|---|---|
| Synonym | Bestatin hydrochloride Bestatin hydrochloride N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride |
| MDL Number | MFCD00058004 |
| PubChem Substance ID | 253659625 |
| Beilstein Registry Number | 4628066 |
| CAS Number | 65391-42-6 |
| Reaxys-RN | 5840390 |
| Chemical Name Translation | 乌苯美司盐酸盐 |
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分类
- {SNA} A to C,
- A to C, Amino Acid Derivatives, Aminopeptidase, Aminopeptidase P, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, B, Bioactive Small Molecules, Biochemicals and Reagents, Broad Spectrum Inhibitors of Proteolytic Enzyme Classes, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure Class, Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Inhibits an Enzyme, L to O, Leucine Aminopeptidase, Leucine aminopeptidase, cytosol,
相关文献及参考
- [2]. Qian X, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2016 May-Jun;23(3):e680-9.
- [3]. Lis M, et al. The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised mice. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):133-8
- [4]. Poloz Y, et al. Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum. Eukaryot Cell. 2012 Apr;11(4):545-57
- 1. Jia, M.R., et al., The Analgesic Activity of Bestatin as a Potent APN Inhibitor Front. Neurosci. 4 , 50, (2010) 摘要
- Gardiner, D.L., et al. J. Biol. Chem. 281 , 1741-1745, (2006) 摘要
- Jia, M.R., et al., The Analgesic Activity of Bestatin as a Potent APN Inhibitor Front. Neurosci. 4 , 50, (2010) 摘要
- Shin, Y.P., et al., Antimicrobial Activity Of A Halocidin-derived P
