2,5-Dioxopyrrolidin-1-Yl 2-Iodoacetate 2,5-二氧吡咯烷-1-基-2-碘乙酸酯
CAS 39028-27-8 MFCD00058451
化学结构图
SMILES: O=C(CI)ON1C(=O)CCC1=O
化学属性
| Mol. Formula | C6H6INO4 |
|---|---|
| Mol. Weight | 283 |
| Melting Point | 145-149 |
别名和识别编码
| Chemical Name | 2,5-Dioxopyrrolidin-1-Yl 2-Iodoacetate |
|---|---|
| MDL Number | MFCD00058451 |
| PubChem Substance ID | 57654310 |
| CAS Number | 39028-27-8 |
| Reaxys-RN | 1213727 |
| Synonym | 碘乙酸 N-羟基琥珀酰亚胺酯 |
| Chemical Name Translation | 2,5-二氧吡咯烷-1-基-2-碘乙酸酯 |
| Beilstein Registry Number | 1213727 |
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分类
- Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Crosslinkers, Crosslinking, Heterobifunctional Cross-Linking Reagents, Linkers and Crosslinkers, Peptide Chemistry,
- {SNA} Active Esters/
- {SNA} Active Esters/Additives, Amine to Sulfhydryl, Chemical Biology, Chemical Synthesis,
相关文献及参考
- Rector, E.S., et al., A method for the preparation of protein-protein conjugates of predetermined composition. J. Immunol. Methods 24 , 321-336, (1978) 摘要
- Houen, G., et al., Conjugation to preactivated proteins using divinylsulfone and iodoacetic acid. J. Immunol. Methods 181 , 187-200, (1995) 摘要
安全信息
GHS Symbol
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P332+P313
- P302+P350
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
