CAS 103-81-1 MFCD00059193-2-Phenylacetamide 2-苯乙酰胺 TAO{mole}

2-Phenylacetamide 2-苯乙酰胺

CAS 103-81-1 MFCD00059193

化学结构图

SMILES: NC(=O)Cc1ccccc1

化学属性

Mol. Formula	C8H9NO
Mol. Weight	135.17
Melting Point	156°C
Boiling Point	312.2°C at 760 mmHg
Solubility	溶于热水、乙醇，微溶于冷水、乙醚、苯。

别名和识别编码

Chemical Name	2-Phenylacetamide
CAS Number	103-81-1
Alfabeta Name	PHENYLACETAMIDE 2-
MDL Number	MFCD00059193
Synonym	2-Phenylacetamide {LY} 2-Phenylacetamide {} {LY} 2-Phenylacetamide {} {} {LY} 2-Phenylacetamide {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phenylacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Phe
EC Number	203-147-0
Beilstein Registry Number	507886
Reaxys-RN	507886
PubChem Substance ID	7680
Merck Number	7266
Chemical Name Translation	2-苯乙酰胺
Wiswesser Line Notation	ZV1R
LabNetwork Molecule ID	LN00159648
InChI	InChI=1S/C8H9NO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,10)
Canonical SMILES	O=C(N)CC1=CC=CC=C1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

Warnings IRRITANT

RTECSAC7705000

Hazard Codes Xi

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 10,579,1976

GHS Symbol

Signal word

WGK Germany3

Risk Statements

Precautionary statements

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

用途二:该品用作医药、农药、香料的中间体。在医药工业中是青霉素G的培养基和镇静药物苯巴比妥的原料。
Sigma Aldrich:103-81-1(sigmaaldrich)
下游产品:苯乙酸乙酯 --> 敌鼠 --> 苯巴比妥
2-苯乙酰胺价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 P0120 2-苯基乙酰胺 2-Phenylacetamide 500G 3600元 2014/06/02 P0120 2-苯基乙酰胺 2-Phenylacetamide 25G 457元
上游原料:苄基氯 --> 氰化苄 --> 浓盐酸 --> 活性炭(脱色) --> 苯乙酸 --> 二甲胺水溶液 --> 多硫化铵
MOL 文件:103-81-1.mol
TCI Shanghai:2-苯基乙酰胺 2-Phenylacetamide,>;98.0%(T)(103-81-1)
Hazard Note:Irritant
MSDS 信息:α-苯基乙酰胺(103-81-1).msds
用途一:用作青霉素G和苯巴比妥等药物的中间体，也用于有机合成
图谱信息:2-苯乙酰胺(103-81-1)红外图谱(IR1) 2-苯乙酰胺(103-81-1)Raman光谱 2-苯乙酰胺(103-81-1)核磁图( 1 HNMR) 2-苯乙酰胺(103-81-1)质谱(MS) 2-苯乙酰胺(103-81-1)核磁图( 13 CNMR) 2-苯乙酰胺(103-81-1)红外图谱(IR2)
方法一:将苯乙烯、硫磺、液氨和水投入高压釜，于165℃、约6.5MPa压力下反应，然后加热蒸发赶去硫化氢气体，加活性炭脱色、冷却、结晶、甩滤、干燥而得苯乙酰胺。此法可改进为管道化连续生产，将苯乙烯与多硫化铵液按体积比1:2配合，通过高压管道，反应温度为200℃，反应压力为6-7.8MPa，反应时间为1.5h。反应产物的后处理工艺过程与高压釜间歇法相似。原料消耗定额：苯乙烯（99%）1117kg/t、硫磺（98.5%）716kg/t、液氨（99%）539kg/t、活性炭47kg/t。另一种生产方法是将苯乙腈（由氯化苄和氰化钠在二甲胺水溶液中反应得到）在硫酸或盐酸中加热水解。将苯乙腈加入浓盐酸，搅拌溶解，在50℃反应半小时。然后在冷却下缓缓加入水析出结晶，冷却后过滤，用冰水洗涤即得粗品。粗品用碳酸钠溶液洗涤，再用冰水洗涤，干燥后可得较纯的苯乙酰胺。原料消耗定额：氯化苄（95%）1190kg/t、氰化钠（95%）527kg/t、二甲胺（工业品）20kg/t、碳酸钠（工业品）185kg/t、硫酸（92.5%）1760kg/t。
外观性质:白色片状或叶状晶体。