(R)-(+)-α-Methylbenzyl isocyanate (R)-(+)-α-甲基苄基异氰酸酯

CAS 33375-06-3 MFCD00063015

化学结构图

33375-06-3
SMILES: C[C@@H](N=C=O)c1ccccc1

化学属性

Mol. FormulaC6H5CH(CH3)NCO
Mol. Weight147
Refractive indexn20/D 1.513(lit.)
Boiling Point55-56 °C/2.5 mmHg(lit.)
Density1.045 g/mL at 20 °C(lit.)
Flash Point65°C(lit.)
TSCANo

别名和识别编码

Chemical Name(R)-(+)-α-Methylbenzyl isocyanate
Synonym (R)-(+)-alpha-Methylbenzyl isocyanate (R)-(+)-α-甲基苄基异氰酸酯 (R)-(+)-1-苯乙基异氰酸酯
CAS Number33375-06-3
PubChem Substance ID87571689
EC Number251-485-2
Beilstein Registry Number3196930
MDL NumberMFCD00063015
Reaxys-RN3196930
Chemical Name Translation(R)-(+)-α-甲基苄基异氰酸酯
InChIKeyJJSCUXAFAJEQGB-UHFFFAOYSA-N
LabNetwork Molecule IDLN00237989
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分类

  • Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Chiral Resolution Reagents, Chiral Resolving Reagents, Isocyanates, Organic Building Blocks
  • {SNA} Chiral, Chiral Derivatization Reagents, Chiral GC Derivatization Reagents, Derivatization Reagents, Derivatization Reagents HPLC, 分析/色谱, 分析试剂
  • {SNA} Analytical Reagents, Analytical/Chromatography, Chiral, Chiral Derivatization Reagents, Chiral GC Derivatization Reagents, Derivatization Reagents, Derivatization Reagents HPLC

相关文献及参考

  • Reagent for determination of chiral purity of alcohols and amines: Anal. Lett., 3, 323 (1970).

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H330 Fatal if inhaled 吸入致命
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H227 Combustible liquid 可燃液体
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes T Xn Xn,T+
Precautionary statements
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P342+P311
  • P332+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P302+P350
  • P337+P313
  • P403+P233
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P370+P378
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P304+P340+P311
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P301+P310+P330
Signal word Danger {} {} {} {} {TCI}
UN Number 2206 UN2206
Storage condition Moisture Sensitive 0-10 0-10°C
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
  • R23 Toxic by inhalation 吸入有毒
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Packing GroupIII
Hazard Class6.1

系列性分类