(R)-2-Amino-3-(4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl)Propanoic Acid (R)-2-氨基-3-(4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基)丙酸

CAS 51-49-0 MFCD00063056

化学结构图

51-49-0
SMILES: N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O

化学属性

Mol. FormulaC15H11I4NO4
Mol. Weight776.87
Melting Point225 ºC

别名和识别编码

Chemical Name(R)-2-Amino-3-(4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl)Propanoic Acid
CAS Number51-49-0
Synonym 3,3',5,5'-Tetraiodo-D-thyronine D-3,3',5,5'-TETRAIODOTHYRONINE Thyroxine, D- (8CI) D-B-[(3 5-DIIODO-4-HYDROXYPHENOXY)-3 5-DIIODO-PHENYL]ALANINE 3,3′,5,5′-四碘代-D-甲状腺原氨酸 3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-D-丙氨酸 D-T4 右旋甲状腺素 D-2-Amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid (2R)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid D-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]ALANINE D-甲状腺素 D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo- (9CI) O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo- D-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzylalanine 3,3μ,5,5μ-Tetraiodo-D-thyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-D-alanine DEBETROL O-(4-羟基-3,5-二碘苯基)-3,5-二碘-D-酪氨酸 D-thyroxine free acid D-THYROXINE 3-[4-(P-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-D-ALANINE d-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid dextrothyroxine O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo- D-3,5-DIIODO-4-(3',5'-DIIODO-4'-HYDROXYPHENOXY)-PHENYLALANINE
MDL NumberMFCD00063056
Beilstein Registry Number2954910
EC Number200-102-7
Chemical Name Translation(R)-2-氨基-3-(4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基)丙酸
LabNetwork Molecule IDLN00337290
PubChem Substance ID8730
InChIInChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m1/s1
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分类

  • Amino Acids & Derivatives
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,
  • {SA} Chemical Biology, Chemical Synthesis, Peptide Chemistry, Threonine Derivatives, Unnatural Amino Acid Derivatives

产品应用

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相关文献及参考

  • Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976),
  • Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988),
  • Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996),
  • Merck 14 ,9415
  • Beil. 14 ,IV,2373

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Storage condition 2-8°C
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

其他信息

  • D-甲状腺素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xp620086 L-甲状腺素;3,5,3′,5′-四碘-L-甲状腺原氨酸;3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸 1g/瓶 40元
  • Sigma Aldrich:51-49-0(sigmaaldrich)
  • 图谱信息:D-甲状腺素(51-49-0)红外图谱(IR1)
  • F:8-10
  • MSDS 信息:D-2-Amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid(51-49-0).msds
  • MOL 文件:51-49-0.mol

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Threonine Derivatives - Unnatural Amino Acid Derivatives

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