H-Phe(4-Cl)-OH L-4-氯苯丙氨酸
CAS 14173-39-8 MFCD00063065
化学结构图
SMILES:
化学属性
| Mol. Formula | ClC6H4CH2CH(NH2)CO2H |
|---|---|
| Mol. Weight | 199.63 |
| Melting Point | 263 |
别名和识别编码
| Chemical Name | H-Phe(4-Cl)-OH |
|---|---|
| Synonym | L-PCPA 4-氯-L-苯基丙氨酸 4-Chloro-D-phenylalanine; 4-Chloro-3-phenyl-D-alanine |
| CAS Number | 14173-39-8 |
| PubChem Substance ID | 24893091 |
| EC Number | 238-023-5 |
| Beilstein Registry Number | 2416150 |
| MDL Number | MFCD00063065 |
| Chemical Name Translation | L-4-氯苯丙氨酸 |
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分类
- {SNA} Chemical Biology, Chemical Synthesis, Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Peptide Chemistry, Phenylalanine Derivatives, Tryptophan Hydroxylase, Unnatural Amino Acids & Derivatives, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Sma
相关文献及参考
- Yoshino, T., and Yamaguchi, I., Possible involvement of 5-HT 2 receptor activation in aggravation of diet-induced acute pancreatitis in mice. J. Pharmacol. Exp. Ther. 283 , 1495, (1997) 摘要
- Benkert, O., et al., Effect of p-chlorophenylalanine (PCPA) on pituitary hormones and testosterone in the human. Arzneimittelforschung 26 , 1369-1371, (1976) 摘要
- Fratta W, et al., Letter: The effect of D- and L-p-chlorophenylalanine on the metabolism of 5-hydroxytryptamine in brain. J. Pharm. Pharmacol. 25 , 908-909, (1973) 摘要
- Beil. 14 ,IV,1674
- FT-NMR 1 (2), 1185:C / RegBook 1 (2), 1843:N / Structure Index 1 , 295:D:7
安全信息
GHS Symbol
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H301 Toxic if swallowed 吞食有毒
- P301+P310
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R25 Toxic if swallowed 吞咽有毒
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
