CAS 3374-05-8 MFCD00064376-Sodium 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate 1-乙基-7-甲基-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸钠盐 TAO{mole}

Sodium 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate 1-乙基-7-甲基-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸钠盐

CAS 3374-05-8 MFCD00064376

化学结构图

SMILES: CCn1cc(C(=O)[O-])c(=O)c2ccc(C)nc21.[Na+]

化学属性

Mol. Formula	C12
Mol. Weight	254
TSCA	No
Melting Point	>280°
Appearance	powder
Solubility	H2O: 50 mg/mL, clear, faintly yellow

别名和识别编码

Chemical Name	Sodium 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate
MDL Number	MFCD00064376
CAS Number	3374-05-8
Synonym	1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 1,4-Dihydro-1-ethyl-4-oxo-7-methyl-1,8-naphthyridine-3-carboxylic acid sodium salt NALIDIXIC ACID SODIUM GAMMA-IRRADIATEDM OLECULAR BI 1-ETHYL-1,4-DIHYDRO-7-METHYL-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID SODIUM SALT sodiumnilixalate 萘啶酮酸钠 nalidixatesodium sodium 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate NALIDIXIC ACID SODIUM SALT MOLEC 8-naphthyridine-3-carboxylicacid,1-ethyl-1,4-dihydro-7-methyl-4-oxo-sodiu 1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸钠盐 sodiumnalidixate Sodium 1 - ethyl - 1,4 - dihydro - 7 - methyl - 4 - oxo - 1,8 - Sodium 1 - nalidixic acid sodium gamma-irradiatedmolecular NALIDIXIC ACID SODIUM SALT Sodium 1 - ethyl - 1,4 -
PubChem Substance ID	3864541
Beilstein Registry Number	3580062
EC Number	222-159-7
Chemical Name Translation	1-乙基-7-甲基-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸钠盐
LabNetwork Molecule ID	LN00195069
InChI	InChI=1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1

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分类

{SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Biochemicals and Reagents, Chemical Structure Class, Genetic Marker Selection, Inhibits an Enzyme, Interferes with DNA Synthesis, L - Z, Mechanism of Action, Quinolones and Fluoroquinolones, Spectrum of Activity
{SNA} Antibacterial, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Apoptosis and Cell Cycle, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Chemical Structure Class, DNA Repair Regulators, DNA metabolism,
{SNA} Antibacterial,

安全信息

RTECSQN2885500

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

GHS Symbol

Precautionary statements

P342+P311
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Hazard statements

H317 May cause an allergic skin reaction 可能导致皮肤过敏
H302 Harmful if swallowed 吞食有害
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难

WGK Germany3

Signal word

Hazard Codes Xn

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S24 Avoid contact with skin 避免皮肤接触；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S34 None 避免冲击和摩擦；

Risk Statements

R42/43

Storage condition 2-8°C

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Cells - not otherwise specified
DOSE/DURATION           : 900 mg/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   60,287,1987

其他信息

MOL 文件:3374-05-8.mol
Sigma Aldrich:3374-05-8(sigmaaldrich)
F:8-10