Quisqualic acid 使君子氨酸
CAS 52809-07-1 MFCD00069337
化学结构图
SMILES: N[C@@H](CN1OC(=O)NC1=O)C(O)=O
化学属性
| Mol. Formula | C5H7N3O5 |
|---|---|
| Mol. Weight | 189 |
| TSCA | No |
| Melting Point | 185-187° |
别名和识别编码
| Chemical Name | Quisqualic acid |
|---|---|
| CAS Number | 52809-07-1 |
| Synonym | L-Quisqualic Acid 使君子氨酸 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine β-(3,5-二氧代-1,2,4-氧杂重氮烷-2-基)-L-丙氨酸 beta-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine L-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine |
| MDL Number | MFCD00069337 |
| PubChem Substance ID | 24278004 |
| Beilstein Registry Number | 1078734 |
| Merck Number | 14,8085 |
| Chemical Name Translation | 使君子氨酸 |
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分类
- {SNA} AMPA/Kainate Agonists, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, 细胞信号转导和神经科学, 细胞生物学
- {SNA} AMPA/Kainate Agonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Q
- Amino Acids & Derivatives; Heterocycles
- Neurochemicals
产品应用
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相关文献及参考
- [2]. H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.
- Honore, T., et al.: J. Neurochem., 38, 173 (1982),
- Recasens, M., et al.: Neurochem. Int., 13, 463 (1988),
- Schoepp, D., et al.: J. Neurochem., 50, 1605 (1988),
- [1]. Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
- [1]. Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
- [2]. H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.
安全信息
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- H332 Harmful if inhaled 吸入有害
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
