Dicrotophos

CAS 141-66-2 MFCD00072499

化学结构图

141-66-2
SMILES: COP(=O)(OC)O/C(C)=C/C(=O)N(C)C

化学属性

Mol. FormulaC₈H₁₆NO₅P
Mol. Weight237.19
Flash Point100 °C
Density1.176

别名和识别编码

Chemical NameDicrotophos
PubChem Substance ID24868752
EC Number205-494-3
Beilstein Registry Number1880084
MDL NumberMFCD00072499
Synonym (1E)-3-(Dimethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate (E)-2-DIMETHYL-CARBAMOYL-1-METHYLVINYLDIMETHYL PHOSPHATE (e)-phosphoricacid,3-(dimethylamino)-1-methyl-3-oxo-1-propenyldimethylester 2-Dimethyl cis-2-dimethyl-carbamoyl-1-methylvinyl phosphate 3-(DIMETHOXYP 3-(Dimethoxyphosphinyloxy)-N,N dimethylisocrotonamide 3-(Dimethoxyphosphinyloxy)-N,N-dimethyl-cis-crotonam 3-(Dimethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate 3-(dimethylamino)-1-methyl-3-oxo-1-propenyldimethylphosphate 3-(dimethylamino)-1-methyl-3-oxo-1-propenyldimethylphosphate(e)-isomer 3-Hydroxy-N,N-dimethyl-cis-crotonamide dimethyl phosphate 3-Hydroxydimethyl crotonamide dimethyl phosphate 3-hydroxydimethylcrotonamidedimethylphosphate 3-二甲基磷氧基-N,N-二甲基异丁烯酰胺 BIDRIN Di
CAS Number141-66-2
Chemical Name Translation
Merck Number13,3114
Wiswesser Line Notation1OPO&O1&OY1&U1VN1&1 -C
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分类

  • {SNA} Alphabetical Index of Analytical Standards, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, Chromatography, D, DIA - DIC, Environmental Standards, Insecticides, Organophorous, Organophosphate, Pesticide Class, Pesticides & Metabolites, Pesticides Standards, Pesticides, toxic to bees

相关文献及参考

  • Merck: 14,3087

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H300 Fatal if swallowed 吞食致命
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTC3850000
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
Signal word Danger
Hazard Codes T+,N
Risk Statements
  • R24 Toxic in contact with skin 与皮肤接触有毒
  • R50/53
  • R28 Very toxic if swallowed 吞咽极毒
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Packing GroupII
Hazard Class6.1(a)
Storage condition 0-6°C 2-8℃ 4
UN Number 3018
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ASTTA8 ASTM Special Technical Publication.  (American Soc. for Testing
   Materials, 1916 Race St., Philadelphia, PA 19103)  No.1-    1911-
   Volume(issue)/page/year: (680),157,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 90 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 15,239,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 168 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,196,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

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TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 16,403,1985

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2 mmol/L/4H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 20,7,1973

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 150 mmol/L/24H
REFERENCE :
   IARCCD IARC Scientific Publications.  (Geneva, Switzerland)  No.1-26,
   1971-78.  For publisher information, see IAPUDO.  Volume(issue)/page/year:
   10,161,1974

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 300 umol/L
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 8,939,1981

其他信息

  • 外观性质:黄色至棕色液体。
  • 灭火剂:砂土、干粉、泡沫
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 类别:农药
  • 毒性分级:高毒
  • 中毒症状:急性中毒多在12小时内发病,口服立即发病。轻度:头痛、头昏、恶心、呕吐、多汗、无力、胸闷、视力模糊、胃口不佳等,全血胆碱酯酶活力一般降 至正常值的70-50%。中度:除上述症状外还出现轻度呼吸困难、肌肉震颤 、瞳孔缩小、精神恍惚、行走不稳、大汗、流涎、腹疼、腹泻。重者还会出现昏迷、抽搐、呼吸困难、口吐白沫、大小便失禁,惊厥,呼吸麻痹。
  • MSDS 信息:百治磷(141-66-2).msds
  • 可燃性危险特性:明火可燃; 受热分解有毒氧化磷、氯化物气体
  • 注意事项:在我国未登记
  • 职业标准:STEL 1 毫克/立方米
  • 急救治疗:[1]用阿托品1~5mg皮下或静脉注射(按中毒轻重而定) [2]用解磷定0.4-1.2g静 脉注射(按中毒轻重而定) [3]禁用吗啡、茶硷、吩噻嗪、利血平。 [4]误服立即引吐、洗胃、导泻(清醒时才能引吐)。
  • Sigma Aldrich:141-66-2(sigmaaldrich)
  • MOL 文件:141-66-2.mol
  • 急性毒性:口服-大鼠 LD50: 13 毫克/公斤; 口服-小鼠 LD50: 13 毫克/公斤

系列性分类


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