1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one 1,7,7-三甲基双环[2.2.1]庚烷-2-酮

CAS 76-22-2 MFCD00074738

化学结构图

76-22-2
SMILES: CC12CCC(CC1=O)C2(C)C

化学属性

Mol. FormulaC10H16O
Mol. Weight152.23
Boiling Point204
Melting Point175-177
Vapor Density5.2 (vs air)
Vapor Pressure4 mmHg ( 70 °C)
Autoignition Point870 °F
Density0.992
Flash Point64.44°C
SolubilitySolubility in water: 1.5 g/L (20°C) Solubility in other solvents: at 25°C 1 g dissolves in 1 ml Alcohol, 1 ml Ether, 0.5 ml Chloroform, 0.4 ml Benzene, 0.4 ml Acetone, 1.5 ml Turpentine oil, 0.5 ml Glacial acetic acid.
TSCAYes
Stability对湿度敏感

别名和识别编码

Chemical Name1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
Synonym (±)-樟脑 (±)-樟脑 1,7,7-三甲基二环[2.2.1]庚烷-2-酮 (+/-)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one (+/-)-樟脑,96% (±)-樟脑(合成) 1,7,7-Trimethylbicyclo(2.2.1)-2-heptanone 1,7,7-三甲基二环[2.2.1]庚烷-2-酮 2-Bornanone 2-Camphanone 2-Kamfanon 2-Keto-1,7,7-trimethylnorcamphane Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl- Bornane, 2-oxo- Camphor {hazard_com} Camphor, natural Camphor, synthetic DL-2-Bornanone Formosa camphor Gum camphor Huile de camphre Japan camphor Kampfer Laurel camphor Matricaria camphor Norcamphor, 1,7,7-trimethyl- 合成樟脑,2-莰酮,樟脑醑,1,7,7-三甲基二环[2.2.1]庚烷-2-酮 合成樟脑;2-莰酮;樟脑醑;1,7,7-三甲基二环[2.2.1]庚烷-2-酮;柏木精脑 柏木精脑 樟脑
CAS Number76-22-2
EC Number200-945-0
Beilstein Registry Number1907611
MDL NumberMFCD00074738
PubChem Substance ID2537
Reaxys-RN1907611
Merck Number1732
Chemical Name Translation1,7,7-三甲基双环[2.2.1]庚烷-2-酮
Wiswesser Line NotationL55 A CVTJ A1 A1 B1
InChIInChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3
LabNetwork Molecule IDLN00193099
Canonical SMILESO=C1C(C2(C)C)(C)CCC2C1
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分类

  • {SA} A-D, Alphabetical Listings, C-D, Flavors and Fragrances, Kosher Certified Products
  • {SNA} Artemisia vulgaris, Building Blocks, C10, Carbonyl Compounds, Chemical Synthesis, Curcuma longa (Turmeric), Elettaria Cardamomum (Cardamom), Ketones, Lavandula angustifolia (Lavendar tea), Melaleuca alternifolia, Nutrition Research, Ocimum basilicum (Basil), Organic Building Blocks, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), Terpenes and Terpenoids (Isoprenoids), Zingiber officinale (Ginger), 细胞生物学
  • {S
  • {SNA} A - D, A-F, All Alphabetical

产品应用

  • 微量分析和气相色谱参比样品。纤维素酯和醚的增塑剂,炸药,烟火,杀虫剂,制造赛璐珞。

相关文献及参考

  • Merck: 14,1732 Beilstein:7,135
  • Merck: 14,1732

安全信息

GHS Symbol
WGK Germany1
Hazard Codes 4.1 F,Xn Xn
Hazard statements
  • H228 Flammable solid 易燃固体
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H302+H332
  • H371 May cause damage to organs 可能导致器官损伤
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSEX1234000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P350
  • P302+P352+P333+P313+P362+P364
  • P305+P351+P338
  • P337+P313
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
UN Number 2717 UN2717
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S37 Wear suitable gloves 戴适当手套;
Packing GroupIII
Risk Statements
  • R11 Highly flammable 非常易燃
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C 密封保存。
Hazard Class4.1
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 65,275,1939

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavi

TYPE OF TEST            :

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 30,857,1954

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 224,157,1989

其他信息

  • 有特殊气味,味苦并有清凉感。在空气中逐渐挥发。能溶于乙醇、醚、氯仿、苯、甲醇、丙酮、乙酸和二氧化硫,溶于浓矿酸、酚、液氨和亚硫酸。半数致死量(小鼠,腹腔)3000mg/kg。
  • Camphor is a novel carbon nanotube precursor.

系列性分类


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