4-Bromo-calcium Ionophore A23187
CAS 76455-48-6 MFCD00077667
化学结构图
SMILES: CNC1C(Br)=CC2OC(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC=2C=1C(O)=O
化学属性
| Mol. Formula | C29H36BrN3O6 |
|---|---|
| Mol. Weight | 602.52 |
别名和识别编码
| Chemical Name | 4-Bromo-calcium Ionophore A23187 |
|---|---|
| Synonym | 4-Bromo-A23187 4-Bromo-calcimycin 4-Bromo-calcium Ionophore A23187 |
| MDL Number | MFCD00077667 |
| PubChem Substance ID | 24891982 |
| CAS Number | 76455-48-6 |
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分类
- Calcium Ionophores, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Signaling
- {SA} Calcium Ionophores, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Signaling
- {SNA} Antibiotics A to Z, Antibiotics A-F, Interferes with Cell Membrane Permeability (Ionophores), Mechanism of Action, 抗生素, 生化试剂
- {SNA} Calcium Ionophores, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Signaling
- {SNA} Calcium Ionophores, Calcium Signaling Research Tools, Intracellular Calcium Signaling, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- Wang, E., et al., Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin. Biophys. J. 75 , 1244-1254, (1998) 摘要
- Deber, C.M., et al., Bromo-A23187: a nonfluorescent calcium ionophore for use with fluorescent probes Anal. Biochem. 146 , 349-352, (1985)
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H332 Harmful if inhaled 吸入有害
- H315 Causes skin irritation 会刺激皮肤
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
