Calmidazolium Chloride 钙调蛋白抑制剂
CAS 57265-65-3 MFCD00077679
化学结构图
SMILES: [Cl-].ClC1=CC(Cl)=CC=C1COC(C[N+]1=CN(C=C1)C(C1C=CC(Cl)=CC=1)C1C=CC(Cl)=CC=1)C1C=CC(Cl)=CC=1Cl
化学属性
| Mol. Formula | C31H23Cl7N2O |
|---|---|
| Mol. Weight | 688 |
别名和识别编码
| Chemical Name | Calmidazolium Chloride |
|---|---|
| Synonym | 1-[bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride 1-[Bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride R 24571 钙调蛋白抑制剂 1-[Bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride 1-[bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride R 24571 |
| MDL Number | MFCD00077679 |
| PubChem Substance ID | 24278023 |
| Beilstein Registry Number | 6470244 |
| CAS Number | 57265-65-3 |
| Chemical Name Translation | 钙调蛋白抑制剂 |
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分类
- {SNA} A to C, Calcium Antagonists, Calmodulin-regulated enzymes, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Intracellular Calcium Signaling, PI3K-Akt-mTOR Enzyme Regulators, 生化试剂, 癌症研究, 细胞信号转导和神经科学, 细胞生物学, 肿瘤生长调节, 酶、抑制剂和底物
- {SNA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Calcium Antagonists, Calmodulin-regulated enzymes, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates,
相关文献及参考
- 1. Sunagawa, M., et al., Direct block of Ca 2+ channels by calmidazolium in cultured vascular smooth muscle cells J. Cardiovasc. Pharmacol. 34 , 488-494, (1999) 摘要
- Fischer, T.H., et al., An investigation of functional similarities between the sarcoplasmic reticulum and platelet calcium-dependent adenosinetriphosphatases with the inhibitors quercetin and calmidazolium. Biochemistry 26 , 8024-8030, (1987) 摘要
- Ichikawa, M., et al., Anticalmodulin drugs block the sodium gating current of squid giant axons. J. Membr. Biol. 120 , 211-222, (1991) 摘要
- Tatsumi, R., et al., A Role For Calcium-calmodulin In Regulating Nitric Oxide Production During Skeletal Muscle Satellite Cell Activation. Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009) 摘要
