• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} non-ionic
• {SNA} Cell Culture, Cell Lysis Reagents, Conjugates, Core Bioreagents, Detergents, Detergents A to M, Detergents by Applications, Diagnostic Applications, Electrophoresis Chromatography, Enzymology, Membrane Protein Solubilization, Molecular Biology, Non-Ionic Detergents, Research Essentials, Signal Transduction Research Tools, Sterol Lipids, 去垢剂, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 脂类
• {SNA} Cell Cul
• {SNA} Cell Culture, Cell Lysis Reagents, Conjugates, Core Bioreagents,

产品应用

• ⑴. 可燃, 火场排出辛辣刺激烟雾。
• ⑵. 利用沉淀反应测定血浆、胆汁和组织中的胆甾醇。
• ⑶. 用作较高级醇类和酚类、硫酚类的试剂。
• ⑷. 在生化研究中可作为去垢剂和脱溶剂处理分离的线粒体，溶解线粒体外膜。
• 利用沉淀反应测定血浆、胆汁核组织的胆甾醇。也用作较高级醇类核酚类、硫酚类的试剂。

相关文献及参考

• Merck: 14,3161 Beilstein:19(3/4)1243
• Merck 14 ,3161
• Prehm, S., et al., A mild purification method for polysaccharide binding membrane proteins: phase separation of digitonin extracts to isolate the hyaluronate synthase from Streptococcus sp. in active form. Protein Expr. Purif. 7 , 343-346, (1996) 摘要
• Liu, J., et al., Use of digitonin-permeabilized cells in studies of steroid receptor subnuclear trafficking. Methods 19 , 403, (1999) 摘要
• Nock, B., Extracti-Gel D chromatography is a simple efficient method for removing digitonin during receptor purification: application to the κ 1 opioid receptor. J. Neurosci. Methods 50 , 353, (1993) 摘要

安全信息

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LD10 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,749,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 12,815,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >50 mg/kg
TOXIC EFFECTS :

{ha

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 250 ppb
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 407,186,1983

其他信息

• ⑴. 该物质对环境可能有危害，对水体应给予特别注意。