Neomycin sulfate Neomycin硫酸盐
CAS 1405-10-3 MFCD00037007
化学结构图
SMILES: NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O.O=S(=O)(O)O
化学属性
| Mol. Formula | C23H46N6O13 |
|---|---|
| Mol. Weight | 909 |
| Solubility | H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days. |
| Appearance | powder |
| Refractive index | 56 ° (C=10, H2O) |
| Melting Point | >187 |
别名和识别编码
| Chemical Name | Neomycin sulfate |
|---|---|
| CAS Number | 1405-10-3 |
| Synonym | FRADIOMYCIN SULFATE NEOMYCIN SULFATE SALT otobiotic mycigient 新霉素 硫酸盐 lidamycincreme Neomycin sulfate NEOMYCIN SULPHATE 硫酸新霉素 usafcb-19 mycaifradinsulfate NEOMYCIN SULFATE, GAMMA-IRRADIATED neofracin quintess-n mycifradin-n neobiotic newfrancef neomix 硫酸新霉素细胞培养试剂 硫酸新霉素BP级 Mycifradin sulfate; O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy sulfate 硫酸新霉甲酯 bykomycin neo-mantlecreme 新霉素 三硫酸盐 水合物 |
| PubChem Substance ID | 197162 |
| EC Number | 215-773-1 |
| MDL Number | MFCD00037007 |
| Chemical Name Translation | Neomycin硫酸盐 |
| Merck Number | 6454 |
| LabNetwork Molecule ID | LN02127202 |
| Beilstein Registry Number | 9468364 |
| InChI | InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1 |
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信息真实价格透明
资金保障
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分类
- {SNA} APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, Alphabetical Index of Analytical Standards, Aminoglycosides, Analytical Standards, Analytical/Chromatography, Antibiotics, Chemical Structure, Chromatography, Clinical Standards, N, NA - NI, Neomycin, Pharmaceutical Standards
- {SNA} Aminoglycosides, Antibacterial, Antibiotic powders, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Chemical Structure Class, Core Bioreagents, Genetic
产品应用
- Neomycin is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
相关文献及参考
- [2]. Hu GF. Neomycin inhibits angiogenin-induced angiogenesis. Proc Natl Acad Sci U S A. 1998;95(17):9791-9795.
- Merck 14 ,6454
- [1]. Sasseville D. Neomycin. Dermatitis. 2010;21(1):3-7.
- [1]. Sasseville D. Neomycin. Dermatitis. 2010;21(1):3-7.
- [2]. Hu GF. Neomycin inhibits angiogenin-induced angiogenesis. Proc Natl Acad Sci U S A. 1998;95(17):9791-9795.
安全信息
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- R22 Harmful if swallowed 吞咽有害
- R42/43
GHS Symbol
其他信息
- 上游原料:氢氧化铵 --> 硫酸铵 --> 硫酸氢钠
- 海关编码:29419000
- F:8
- 产品分类:氨基糖苷类抗生素药物
- 图谱信息:硫酸新霉素(1405-10-3)红外图谱(IR1) 硫酸新霉素(1405-10-3)红外图谱(IR2)
- 硫酸新霉素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 U1458009 硫酸新霉素 200mg 1990元
- 用途四:在没有影响神经元Na+/Ca2+ 反向转运蛋白（antiporter）的情况下阻断电压灵敏的Ca2+ 通道。结合到核糖体30S 和 50S 亚单位引起蛋白错误编码；在蛋白合成起间抑制起始和延长。抗菌谱: 革兰氏阴性和阳性细菌。
- MOL 文件:1405-10-3.mol
- 外观:白色或类白色粉末
- 用途二:一种氨基糖苷类抗生素，对革兰氏阴性菌和革兰氏阳性菌有极好的杀灭作用。广泛应用于医药和兽药领域.
- 用途一:为广谱抗生素，对金葡菌、白喉杆菌和炭疽杆菌作用好
- EPA Substance Registry System:1405-10-3(EPA Substance)
- 鉴别:ABC成正反映
