Cefoxitin Sodium 头孢西丁钠盐
CAS 33564-30-6 MFCD00079042
化学结构图
SMILES: [Na+].CO[C@]1(NC(=O)CC2=CC=CS2)[C@H]2SCC(COC(N)=O)=C(C([O-])=O)N2C1=O
化学属性
| Mol. Formula | C16H16N3NaO7S2 |
|---|---|
| Mol. Weight | 449.43 |
别名和识别编码
| Chemical Name | Cefoxitin Sodium |
|---|---|
| CAS Number | 33564-30-6 |
| Synonym | Cefoxotin sodium Mefoxitin Merxin 头孢西丁 钠盐 Monosodium cefoxitin ######## Mefoxin Cefoxitin sodium salt Cenomycin |
| MDL Number | MFCD00079042 |
| PubChem Substance ID | 24892725 |
| EC Number | 251-574-6 |
| Chemical Name Translation | 头孢西丁钠盐 |
| Wiswesser Line Notation | T46 ANV ES GUTJ CO1 G1OVZ HVO CMV1- BT5SJ &-NA- |
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分类
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, C, CA - CG, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
- Alphabetic, Analytical Standards, Analytical/Chromatography, C, CA - CG, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
- {SNA} Additional Standards, Analytical Standards,
产品应用
- Semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to ?-lactamase inactivation. An antibacterial.
相关文献及参考
- Wallick, H., et al.: Antimicrob. Agents Chemother., 5, 25 (1974),
- Brenner, G.S., et al.: Anal. Profiles Drug Subs., 11, 169 (1982),
- Merck 14 ,1936
安全信息
GHS Symbol
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,629,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8580 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 11,181,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 22,123,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,629,19
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE
