Alginic Acid Sodium Salt 海藻酸钠

CAS 9005-38-3 MFCD00081310

化学结构图

9005-38-3
SMILES:

化学属性

Mol. WeightN/A
TSCAYes
Mol. FormulaN/A
Appearance 无色或淡黄色细丝颗粒或粉末状固体。 不溶于乙醇,乙醚和氯仿等有机溶剂。 powder
Stability对湿度敏感
Melting Point99 °C

别名和识别编码

MDL NumberMFCD00081310
CAS Number9005-38-3
Synonym Sodium alginate {LY} Sodium alginate {} {LY} Sodium alginate {} {} {LY} Sodium alginate {} {} {} {LY} Sodium alginate {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sodium alginate {} {} {} {} {} {} {} {} {} {} {} {}
Merck Number14,241
EC Number232-680-1
Chemical NameAlginic Acid Sodium Salt
Chemical Name Translation海藻酸钠
Canonical SMILES[Sodium alginate]
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分类

  • {SNA} Anionic Surfactants, Carbohydrates, Carbohydrates and Starches, Fucus vesiculosus, Functional Foods, Natural Polymers and Biopolymers, Phytochemicals by Plant (Food/Spice/Herb), Polymer Additives,
  • {SA} Carbohydrate, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics
  • {SNA} Carbohydrate,

产品应用

  • 稳定剂。增稠剂。作人造半透膜。媒染剂。
  • 生化级用于固定细胞、酶;如海藻酸钠法固定化谷氨酸脱羧酶。海藻酸基质可以通过添加螯合剂而液化。

相关文献及参考

  • Merck: 14,241

安全信息

WGK Germany1
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSAZ5820000
Hazard Codes Xi
Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture Store at RT. {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed stora
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
Precautionary statements
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Blood - hemorrhage
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 12,129,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,381,1974

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effect

其他信息

  • 方法三:方法一、以干海带或干马尾藻为原料 浸泡、固色 取干海带120kg或干马尾藻180kg(一般含胶量大于15%),去泥沙等物,加清水(或含甘露醇小于2%的海藻洗液)2-3t,常温浸泡两小时,用水搓洗,洗净甘露醇等杂质,溶液回收甘露醇。洗涤干净的原料,加入原料干重15倍量的1%甲醛溶液,在室温下浸16-24h,已固色的原料用水冲洗1次,酌情切碎。 干海带(或干马尾藻)[水,HCHO]→[16-24h]固色海带碎末 消化 按原料干重取10-15倍量的10-15g/L(1%-1.5%)碳酸钠溶液,蒸汽加温至40-45℃(春、秋)或30-40℃(夏)或50-55℃(冬)(马尾藻65-70℃),再加已固色的原料,保温消化4h,至物料变成糊状,达消化终点,得糊状胶液。 固色海带[Na2CO3]→[加温消化4h]糊状胶液 沉淀 将糊状胶液,用清水按原料干重60-70倍稀释,搅拌均匀,室温静置沉淀16-20h,放出上层清液,通过80-100目丝绢滤过后,用细布袋过滤,得澄清海藻酸钠液。下层沉渣压出的胶液再沉淀4-8h,细布袋精滤,弃渣,合并澄清滤液得胶液。 酸凝 将澄清胶液20000L以细流状加入盐酸60-70L(或硫酸40-50L),稍加搅拌,静置片刻,pH达1-1.5,下部放出的废酸液澄清透明即达终点。酸凝后的海藻酸用水冲洗至洗液pH达1.5-2,装袋,自滤片刻,压榨得海藻酸。 上清液[HCl]→[pH1-1.5]海藻液 漂白、降解 取海藻酸(水分低于90%)200kg捣碎,加入体积分数为90%乙醇80-100kg及300g/L(30%)NaOH液10-14L,得海藻酸钠浆,中和时间不超过8h,控制pH7-8。中和完毕后,加次氯酸钠液(含量30-50g/L) 24-30L漂白,然后用亚硫酸钠液(含量20-27g/L)5-7L左右还原多余的次氯酸钠,控制pH8,至淀粉碘化钾不显蓝色为止,滤去乙醇,甩干,得低聚海藻酸钠。 海藻酸[乙醇,NaOH]→[8h, pH7-8]海藻酸钠浆[NaClO, Na2SO3]→[pH8]低聚海藻酸钠 干燥、粉碎 取湿低聚海藻酸钠,均匀的撒置在烘盘内,在60-80℃,2-8h,烘干,粉碎,得白色低聚海藻酸钠成品。 湿低聚海藻酸钠[60-80℃, 2-8h]→低聚海藻酸钠成品 方法二、以海带(掺1/3海藻)为原料的制法 浸泡、固色、消化、沉淀 海带(掺1/3海藻),去泥沙等物,加清水浸泡两小时,洗净,投入原料干重10倍量的0.8%甲醛溶液浸泡固色16h以上(夏天短,冬天长)。按原料干重取10-15倍量的10-15g/L(1%-1.5%)碳酸钠,升温至80℃左右,再加原料,保温50-60℃,60r/min搅拌消化3-4h,消化液用原料干重60-70倍量的水稀释,用恩氏黏度计测定溶液黏度110Pa·s为准,沉淀8h。放出上清液,通过80-100目丝绢滤过,下层沉淀压滤,去渣,压滤的胶液再沉淀4-8h,合并滤液,得上清液。 海带(掺1/3海藻)[水,HCHO]→[常温18h]固色物[Na2CO3, 水]→[50-60℃, 3-4h]糊状物[水]→[8h]上清液 酸凝、中和、干燥 取澄清胶液边过滤流入酸聚桶中,边加盐酸,胶液管与酸管双管碰在一起,酸凝迅速,不超过半小时,pH控制在1-1.5,酸凝后的海藻酸用水冲洗,洗液pH1.5-2,装袋,自滤片刻后,压滤,得海藻酸,含水量85%-90%,再将海藻酸拌碎,加入适量纯碱中和成海藻酸钠浆,时间不超过8h,中和均匀后,铺在玻璃板上直接于70-80℃烘干,不超过90℃,粉碎,即得海藻酸钠粗品。 上清液[HCl]→[pH1-1.5]海藻酸[水]→[pH1.5-2]海藻酸[Na2CO3]→[pH7-8, 8h]海藻权钠浆→[70-80℃]粗制品 漂白、降解 取软水280L加热至60-70℃,搅拌均匀的撒入海藻酸钠10kg,继续加热、搅拌,完全溶解,然后均匀的加入适量次氯酸钠液,充分搅拌。反应过程中,胶液黏度逐渐下降,反应液颜色变浅,黏度合格后,立即加入2kg活性炭,搅拌20min,脱色,趁热压滤,得澄清滤液。 粗制品[水,Na2CO3, 活性炭]→[60-70℃]澄清滤液(低聚海藻酸钠) 沉淀、干燥 滤液通人盛有80%乙醇的沉淀缸中乙醇:滤液=2:1(体积比)沉淀,加活性炭1kg,脱色,压滤。将所得沉淀物离心甩干乙醇,取出纤维状物捣碎,以90%-95%乙醇浸泡,充分脱水,再次甩干,检查表面有无异物,如有刮去表层,再制颗粒,65℃以下干燥,即得低聚海藻酸钠成品。相对分子质量为20000-31000。 低聚海藻酸钠[乙醇]→[65℃以下]低聚海藻酸钠成品 制剂 取低聚海藻酸钠4g,葡萄糖50g,氯化钠3g,枸橼酸0.015g,磷酸氢二钠(Na2HPO

系列性分类