D-Amino acid oxidase D-氨基酸氧化酶

CAS 9000-88-8 MFCD00081546

化学结构图

9000-88-8
SMILES:

别名和识别编码

Synonym D-AAO D-AAO D-Amino acid: oxygen oxidoreductase (deaminating) D-Amino Acid Oxidase from porcine kidney D-Amino acid: oxygen oxidoreductase (deaminating)
MDL NumberMFCD00081546
CAS Number9000-88-8
EC Number232-563-5
Chemical NameD-Amino acid oxidase
Chemical Name TranslationD-氨基酸氧化酶
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分类

  • {SNA} 1.4.x.x Acting on CH-NH2, 1.x.x.x Oxidoreductases, Biochemicals and Reagents, Chemical Synthesis, Enzyme Class Index, Enzyme-Mediated Synthesis, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, General Metabolic Enzymes A-H, Metabolomics, Oxidoreductases, Specialty Synthesis
  • 1.4.

产品应用

  • D-amino acid oxidase (DAO) is a potential target molecule for the treatment of chronic pain and schizophrenia. D-amino acid oxidase is used to oxidize D-amino acids to their corresponding imino acids.

相关文献及参考

  • Richard P. Swenson, Charles H. Williams, The Primary Structure of D-Amino Acid Oxidase from Pig Kidney J. Biol. Chem. 257(15) , 8817-8823, (1982)
  • Merck 14 ,414

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Storage condition 储存温度 2-8°C

其他信息

  • D-amino acid oxidase is a flavoprotein. D-amino acid oxidase derived from porcine liver has been extensively studied. The enzyme is isolated as a stable crystalline complex with benzoate, from which the holo- and apoenzyme may be prepared. The benzoate is readily exchanged for a substrate. D-amino acid oxidase in the presence of molecular oxygen oxidatively deaminates D-amino acides to corresponding α-keto-acids:RCHNH2COOH + O2 + H2O →RCOCOOH + NH3 + H2O2

系列性分类


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