Pepsin A 蛋白酵素

CAS 9001-75-6 MFCD00081840

化学结构图

9001-75-6
SMILES:

化学属性

Mol. FormulaH2
Density1.422
Mol. Weight1
Stability对光线敏感

别名和识别编码

Synonym Elixer lactate of pepsin 胃蛋白酶 Pepsin-Agarose from porcine gastric mucosa Pepsin Pepsini pulvis 胃液素 来源于猪胃 胃蛋白酶 A E.C. 3.4.1 胃液素 来源于猪胃 E.C. 3.4.23.1 胃液素,胃朊酶,蛋白酵素,酸腈酶,胃酶 胃液素 来源于猪胃;胃蛋白酶 A Lactated pepsin elixir 胃液素 来源于猪胃 胃蛋白酶 A 胃蛋白酶 A Pepsin A Lactated pepsin 胃蛋白酶 来源于猪胃粘膜 Pepsin fortior 胃液素;胃朊酶;蛋白酵素;酸腈酶;胃酶
MDL NumberMFCD00081840
CAS Number9001-75-6
EC Number232-629-3
Merck Number7146
Beilstein Registry Number2384789
Chemical NamePepsin A
Chemical Name Translation蛋白酵素
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} 3.4.x.x Peptidases, 3.x.x.x Hydrolases, Antibody Fragmentation, Antibody Modification, Application Index, BRDU 细胞增殖检测试剂, Clinical Chemistry, Core Bioreagents, Core Bioreagents Enzymes, Enzyme Class Index, Enzymes for Diagnostic Kit Manufacturing, Pepsin,
  • {SNA} 3.4.x.x Peptidases

产品应用

  • 本品能使胃酸作用后凝固的蛋白质分解成胨,但不能进一步使之分解成氨基酸。其消化力以含0.2%~0.4%盐酸(PH=1.6~1.8)是为最强。

相关文献及参考

  • Ryle, A.P. Meth. Enzym. Anal. 3rd ed., 5 , 228, (1984)
  • Merck: 14,7146

安全信息

GHS Symbol
WGK Germany1
Precautionary statements
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P332+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P304+P340+P312
  • P302+P350
  • P337+P313
  • P302+P352+P332+P313+P362+P364
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P304+P340
  • P342+P311
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
  • P305+P351+P338+P337+P313
  • P405 Store locked up. 上锁保管。
  • P403+P233
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xn
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSSC6132000
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
Storage condition 2-8℃保存。 储存温度2-8℃ 0-10°C 储存温度-20℃
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 1000 ppm
REFERENCE :
   SFCRAO Collection of Papers Presented at the Annual Symposium on Fundamental
   Cancer Research. (Baltimore, MD)  V.1-29, 1946-76.  For publisher
   information, see AFCPDR.  Volume(issue)/page/year: 23,346,1970

其他信息

  • Pepsin is an acidic protease. Its inactive zymogen precursor, pepsinogen, is produced in the stomach mucosa. There are several pepsins designated A, B, C, and D. Pepsin A, the major component, has a molecular weight of 35,000 daltons and an optimum pH of approximately 1.0 for substrates such as casein or hemoglobin if the substrate is native protein. Pepsin cleaves proteins preferentially at carboxylic groups of aromatic amino acids such as phenylalanine and tyrosine. It will not cleave at bonds containing valine, alanine or glycine. Pepsin is assayed based on the method of Anson J. Gen. Physiol., 22, 79 (1938) using hemoglobin as the substrate. Pepsin is unstable above pH 6.
  • 由胃粘膜主细胞分泌的胃蛋白酶原,在PH 1.5~5.0条件下,经活化提取而成。为白色或淡黄色粉末。分子量约34500。易溶于水呈不同程度的乳白色,几乎不溶于醇、氯仿和醚。水溶液加热至70℃或在碱性溶液中其活性很快破坏,但其干燥品可耐热至100℃,具吸湿性,微酸及盐味。

系列性分类


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