CAS 5875-06-9 MFCD00083467-2-(Diethylamino)Ethyl 3-Amino-4-Propoxybenzoate Hydrochloride 2-二乙基氨基乙基-3-氨基-4-丙氧基-苯甲酸酯盐酸盐 TAO{mole}

2-(Diethylamino)Ethyl 3-Amino-4-Propoxybenzoate Hydrochloride 2-二乙基氨基乙基-3-氨基-4-丙氧基-苯甲酸酯盐酸盐

CAS 5875-06-9 MFCD00083467

化学结构图

SMILES: CCCOc1ccc(C(=O)OCCN(CC)CC)cc1N.Cl

化学属性

Mol. Formula	C16H26N2O3.HCl
Mol. Weight	330.85
Density	1.065
Solubility	DMSO 12 mg/mL Water 66 mg/mL Ethanol <1 mg/mL
Melting Point	182.0 to 186.0 deg-C

别名和识别编码

Chemical Name	2-(Diethylamino)Ethyl 3-Amino-4-Propoxybenzoate Hydrochloride
CAS Number	5875-06-9
Synonym	ophthetic PROXYMETACAINEHYDROCHLORIDE/PROPARACAINE 丙美卡因盐酸盐 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride benzoicacid,3-amino-4-propoxy-,2-(diethylamino)ethylester,monohydrochlorid ophthainehydrochloride Ophthaine hydrochloride Proxymetacaine hydrochloride 3-Amino-4-propoxybenzoic Acid 盐酸丙美卡因 ophthain benzoicacid,3-amino-4-propoxy-,2-(diethylamino)ethylester,hydrochloride chibro-heracaine ProxymetacaineHCL2-CHLORO-9-(2'-DEOXY-2'-FLUORO-B-D-ARABINOFURANOSYL)ADENINE PROPARACAINE HCL Alcaine 2-Diethylaminoethyl 3-amino-4-propoxybenzoate hydrochloride 烟酸丙美卡因 beta-(Diethylamino)ethyl 3-amino-4-n-propoxybenzoate hydrochloride 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester; Ophthaine; Proparacaine 2-二乙基氨基乙基 3-氨基-4-丙氧基-苯甲酸酯盐酸盐 PROPARACAINE HYDROCHLORIDE alcaine PROXYMETACAINE(2-DIETHYLAMINOETHYL-3-AMINO-4-PROPOXYBENZOATE HYDROCHLORIDE) 盐酸丙美卡因; 丙美卡因盐酸盐; 2-二乙基氨基乙基 3-氨基-4-丙氧基-苯甲酸酯盐酸盐 beta-(diethylamino)ethyl3-amino-4-n-propoxybenzoatehydrochloride Proxymetacaine Proparacaine hydrochloride 2-diethylaminoethyl 3-amino-4-propoxy-benzoate hydrochloride Keracaine 丙美卡因盐酸盐 Ophthain 3-amino-4-propoxybenzoicacid2-(diethylamino)ethylesterhydrochloride keracaine
MDL Number	MFCD00083467
PubChem Substance ID	253662420
EC Number	227-541-7
Chemical Name Translation	2-二乙基氨基乙基-3-氨基-4-丙氧基-苯甲酸酯盐酸盐
Reaxys-RN	3754950
Merck Number	7807
Wiswesser Line Notation	3OR BZ DVO2N2&2 &GH
LabNetwork Molecule ID	LN01310892
InChI	InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

Topical anesthetic (ophthalmic).

安全信息

RTECSDG3065000

GHS Symbol

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312+P330
P305+P351+P338
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H319 Causes serious eye irritation 严重刺激眼睛
H332 Harmful if inhaled 吸入有害

WGK Germany3

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Hazard Codes Xn

Risk Statements

R36 Irritating to eyes 刺激眼睛
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

Storage condition 储存温度-20°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3371 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 123,269,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 40,133,1982

其他信息

Proparacaine HCl是电压门控的钠离子通道的拮抗剂，ED50是3.4 mM。
MOL 文件:5875-06-9.mol
Sigma Aldrich:5875-06-9(sigmaaldrich)