4-Formylaminoantipyrine 4-甲酰氨基安替比林
CAS 1672-58-8 MFCD00085457
化学结构图
SMILES: Cc1c(NC=O)c(=O)n(-c2ccccc2)n1C
化学属性
| Mol. Formula | C12H13N3O2 |
|---|---|
| Mol. Weight | 231 |
| Melting Point | 189-192 |
别名和识别编码
| Chemical Name | 4-Formylaminoantipyrine |
|---|---|
| CAS Number | 1672-58-8 |
| Synonym | 4-(Formylamino)antipyrine 4-Formamidoantipyrine 4-formylaminoantipyrine 4-甲酰氨基安替吡啉 N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide N-(1,5-二甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-基)甲酰胺 N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide N-Antipyrinylformamide NSC 60565 |
| MDL Number | MFCD00085457 |
| Beilstein Registry Number | 217665 |
| EC Number | 216-808-3 |
| Alfabeta Name | DIMETHYLOXOPHENYLDIHYDROPYRAZOLYLFORMAMIDE H15322314()-----------,, |
| Chemical Name Translation | 4-甲酰氨基安替比林 |
| LabNetwork Molecule ID | LN00178869 |
| PubChem Substance ID | 72666 |
| InChI | InChI=1S/C12H13N3O2/c1-9-11(13-8-16)12(17)15(14(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3,(H,13,16) |
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分类
- {SNA} APIs & Metabolites, APIs (Active Pharmaceutica
- {SNA} APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, Chromatography, Metamizol & Metabolites, Pharmaceutical Standards
- {SNA} APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, Additional Standards, Analytical Standards, Chromatography, Metamizol Metabolites, Pharmaceutical Standards, 分析/色谱
- {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards L - M, Pharmaceutical Standards, Pharmacopeia Standards
产品应用
- A metabolite of Dipyrone, a nonsteroidal anti-inflammatory drug.
相关文献及参考
- [2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31.
- [3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79.
- Kujubu, D., et al.: J. Biol. Chem., 266, 12866
- [1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther
- [1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther
- [2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Phar
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