2′,7′-Dichlorodihydrofluorescein Diacetate 2,7-二氯荧光素二乙酸酯
CAS 4091-99-0 MFCD00128955
化学结构图
SMILES: CC(=O)Oc1cc2c(cc1Cl)C(c1ccccc1C(=O)O)c1cc(Cl)c(OC(C)=O)cc1O2
化学属性
| Mol. Formula | C24H16Cl2O7 |
|---|---|
| Mol. Weight | 487 |
| Melting Point | 232 |
| Stability | 空气敏感，光敏感 |
别名和识别编码
| Chemical Name | 2′,7′-Dichlorodihydrofluorescein Diacetate |
|---|---|
| CAS Number | 4091-99-0 |
| Synonym | 2′,7′-Dichlorodihydrofluorescein diacetate 2',7'-Dichlorodihydrofluorescein Diacetate 2',7'-Dichlorodihydrofluorescein diacetate 2',7'-dichlorodihydrofluorescein diacetate 2′,7′-Dichlorodihydrofluorescein diacetate DCDHF-DA DCFH DCFH-DA;2,7-二氯二氢荧光素二乙酸酯 H2DCFDA |
| MDL Number | MFCD00128955 |
| PubChem Substance ID | 77718 |
| Beilstein Registry Number | 4610273 |
| Chemical Name Translation | 2,7-二氯荧光素二乙酸酯 |
| InChIKey | PXEZTIWVRVSYOK-UHFFFAOYSA-N |
| LabNetwork Molecule ID | LN00198559 |
| InChI | InChI=1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30) |
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分类
- {SNA} Alphabetical, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Fluorescent Enzyme Substrates, Fluorescent Probes, Labels, Particles and Stains, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Fluorescent Labels & Indicators
- {SNA} Alphabetical, Bioactive Small Molecule Alphabetical Index, Cell Stress, D-DIF, Fluorescent Enzyme Substrates
- Aromatics
- {SNA} Alphabetical, Biochemicals and Reagents, Cell Signaling and Neuroscience, Cell Stress, Fluorescent Enzyme Substrates, Fluorescent Probes, Labels, Particles and Stains, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents, 细
产品应用
- 2',7'-Dichlorodihydrofluorescein as a cell-permeable non-fluorescent probe. It is de-esterified intracellularly and turns to highly fluorescent 2?,7?-dichlorofluorescein upon oxidation.
相关文献及参考
- Baron, C., et al.: J. Agric. Food Chem., 57, 4185 (2009),
- Kjaer, M., et al.: Lipids, 43, 813 (2008),
- Lebel, C., et al.: Chem. Res. Toxicol., 5, 227 (1992),
- [1]. Lyublinskaya OG, et al. Redox environment in stem and differentiated cells: A quantitative approach. Redox Biol. 2017 Aug;12:758-769.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352
- P304+P340
- P305+P351+P338
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
