(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-Tetraen-1-Ol 香叶基香叶醇

CAS 24034-73-9 MFCD00129083

化学结构图

24034-73-9
SMILES: CC(C)CCCC(C)CCCC(C)CCC/C(/C)=C/CO

化学属性

Mol. FormulaC20H34O
Mol. Weight290

别名和识别编码

Chemical Name(2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-Tetraen-1-Ol
CAS Number24034-73-9
Synonym (2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol (E,E,E)- 3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol (E,E,E)-Geranylgeraniol All-trans-Geranylgeraniol all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol trans,trans,trans-G
MDL NumberMFCD00129083
PubChem Substance ID24895120
Beilstein Registry Number1913779
Chemical Name Translation香叶基香叶醇
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分类

  • {SNA} Biochemicals and Reagents, Cancer Metabolism, Cancer Research, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates, Isoprenoids, Key Mevalonate Metabolites Implicated In Cancer,
  • {SNA} Enzyme Inhibitors, Enzyme Inhibitors by Type, Isoprenoids, Prenols, Substrate Analogs, Terpenoids, 代谢组学, 代谢通路, 参与癌症的关键甲羟戊酸代谢物, 生化试剂, 癌症中的甲羟戊酸途径, 癌症代谢, 癌症研究, 细胞生物学, 脂类, 萜类代谢, 酶、抑制剂和底物
  • Biochemicals and Reagents, Cancer Metabolism,

产品应用

  • Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteocl

相关文献及参考

  • Aiuchi, T., et al.: J. Biochem., 124, 300 (1998),
  • Fisher, J.E., et al.: Proc. Natl. Acad. Sci. U.S.A. 96, 133 (1999),
  • Montero, M.T., et al.: J. Immunol., 173, 4936 (2004),
  • 1. Vik, A., et al., Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro Planta Med. 73 , 1410-1412, (2007)
  • Kotti, T.J., et al., Brain cholesterol turnover required for geranylgeraniol production and learning in mice Proc. Natl. Acad. Sci. U. S. A. 103 , 3869-74, (2006) 摘要
  • Kotti, T., et al., Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation Proc. Natl. Acad. Sci. U. S. A. 105 , 11394-9, (2008) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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