Fipexide Hydrochloride 盐酸非哌西特
CAS 34161-23-4 MFCD00133323
化学结构图
SMILES: Cl.O=C(COC1C=CC(Cl)=CC=1)N1CCN(CC2C=C3OCOC3=CC=2)CC1
化学属性
| Mol. Formula | C20H21ClN2O4.ClH |
|---|---|
| Mol. Weight | 425.34 |
别名和识别编码
| Chemical Name | Fipexide Hydrochloride |
|---|---|
| Synonym | 1-(1,3-Benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)acetyl)piperazine 非哌西特 盐酸盐 Attentil |
| MDL Number | MFCD00133323 |
| PubChem Substance ID | 24894906 |
| EC Number | 251-857-4 |
| CAS Number | 34161-23-4 |
| Chemical Name Translation | 盐酸非哌西特 |
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分类
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, F, FA - FL, Forensic and Veterinary Standards, Neat Compounds
相关文献及参考
- [1]. A Marino, et al. Fipexide improvement of cognitive functions in rat: behavioural and neurochemical studies. Pharmacol Res. Mar-Apr 1990;22(2):179-87.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4482 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 499 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4150 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985
