Narasin from Streptomyces auriofaciens

CAS 55134-13-9 MFCD00133653

化学结构图

55134-13-9
SMILES: C[C@]1(CC[C@]2(O1)O[C@]1(C=CC2O)O[C@H]([C@@H](CC)C(=O)[C@@H](C)[C@@H](O)[C@H](C)[C@@H]2O[C@@H]([C@@H](CC)C(O)=O)[C@@H](C)C[C@@H]2C)[C@@H](C)C[C@H]1C)[C@H]1CC[C@](O)(CC)[C@H](C)O1

化学属性

Mol. FormulaC43H72O11
Mol. Weight765.03

别名和识别编码

Chemical NameNarasin from Streptomyces auriofaciens
CAS Number55134-13-9
Synonym A 28086A Narasin A (4S)-4-Methylsalinomycin Monteban Narasin Narasin from Streptomyces auriofaciens C 7819B Antibiotic A-28086 factor A Compound 79891 Narasul Antibiotic A 28086A 4-Methylsalinomycin Antibiotic C 7819B
MDL NumberMFCD00133653
PubChem Substance ID24897476
Wiswesser Line NotationT6XOX DHJ DQ A-& BT6OXTJ C1 E1 FY2&VY1&YQY1&- BT6OTJC1 E1 FY2&VQ&& C-& BT5OXTJ E1 E- FT6OTJ
Beilstein Registry Number1678311
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Heterocycles
  • {SNA} Antibacterial, Antibiotics A to Z, Antibiotics N-S, Interferes with Cell Membrane Permeability (Ionophores), L - Z, Mechanism of Action, Spectrum of Activity, 抗生素, 生化试剂
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Interferes with Cell Membrane Permeability (Ionophores), L - Z, Mechanism of Action, Spectrum of Activity

产品应用

  • Narasin is the main component of a polyether antibiotic complex produced by Streptomyces auriofaciens NRRL 5758 & NRRL 8092. Ionophoric antibiotic which inhibits coccidial infection in poultry and mam

相关文献及参考

  • Berg, D.H., et al.: J. Antibiot., 31, 1 (1978),
  • Ruff, M.D., et al.: Poult. Sci., 59, 2008 (1980),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
Hazard statements
  • H300 Fatal if swallowed 吞食致命
RTECSVO8640000
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T+
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R28 Very toxic if swallowed 吞咽极毒
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >400 mg/m3/30M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VHTODE Veterinary and Human Toxicology.  (American College of Veterinary and
   Comparative Toxicology, Publication Office, Comparative Toxicology,
   Manhattan, KS 66506)  V.19-    1977-  Volume(issue)/page/year: 36,318,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1960 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - food intake (animal)
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   VHTODE Veterinary and Human Toxicology.  (American College of Veterinary and
   Comparative Toxicology, Publication Office, Comparative Toxicology,
   Manhattan, KS 66506)  V.19-    1977-  Volume(issue)/page/year: 36,318,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >10 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - food intake (animal)
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   VHTODE Veterinary and Human Toxicology.  (American College of Veterinary and
   Comparative Toxicology, Publication Office, Comparative Toxicology,
   Manhattan, KS 66506)  V.19-    1977-  Volume(issue)/page/year: 36,318,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 15500 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behaviora

系列性分类


相关产品推荐