Prostaglandin E2 methyl ester

CAS 31753-17-0 MFCD00133789

化学结构图

31753-17-0
SMILES: CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)OC)C(=O)C[C@H]1O

化学属性

Mol. FormulaC21H34O5
Mol. Weight366.55

别名和识别编码

Chemical Name5-Heptenoic acid,7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, methyl ester, stereoisomer
MDL NumberMFCD00133789
PubChem Substance ID24898801
EC Number202-500-6
CAS Number31753-17-0
Synonym PGE2 methyl ester Prostaglandin E2 methyl ester (-)-Prostaglandin E2 methyl ester
Beilstein Registry Number2951095
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分类

  • {SNA} Biochemicals and Reagents, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids, Prostaglandins

安全信息

WGK Germany2
GHS Symbol
Precautionary statements
  • P301+P310
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301 Toxic if swallowed 吞食有毒
  • H312 Harmful in contact with skin 皮肤接触有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSMJ9678000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 2 mg/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 186,67,1973

系列性分类


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