L-Tetrahydrofolic Acid 四氢叶酸
CAS 135-16-0 MFCD00135583
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Cofactor, Cofactors, Folic, Oxidation-Reduction, 代谢组学, 代谢通路, 代谢通路图中的代谢产物和辅酶分子, 叶酸代谢, 生化试剂, 细胞生物学, 酶、抑制剂和底物
- {SNA} Cofactor, Cofactors, Folic, Oxidation-Reduction, 代谢组学, 代谢通路, 代谢通路图中的代谢产物和辅酶分子, 叶酸代谢, 生化试剂, 细胞生物学,
- {SNA} Biochemicals and Reagents, Cofactor, Cofactors, Enzymes, Inhibitors, and Substrates, Folic,
产品应用
- A folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids.
相关文献及参考
- Breaker RR., Prospects for riboswitch discovery and analysis. Mol. Cell. 43 , 867-879, (2011) 摘要
- Fowler B., The folate cycle and disease in humans. Kidney Int. (Suppl.) 78 , S221-229, (2001)
- Graber JR, Breznak JA., Folate cross-feeding supports symbiotic homoacetogenic spirochetes. Appl. Environ. Microbiol. 71 , 1883-1889, (2005) 摘要
- Huang L, Ishibe-Murakami S, et al., Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proc. Natl. Acad. Sci. U. S. A. 108 , 14801-14806, (2011) 摘要
- Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009),
- Ragsdale SW., Catalysis of methyl group transfers involving tetrahydrofolate and B(12). Vitam. Horm. 79 , 293-324, (2008) 摘要
- Scrutton NS, Leys D., Crystal structure of DMGO provides a prototype for a new tetrahydrofolate-binding fold. Biochem. Soc. Trans. 33 , 776-779, (2005) 摘要
- Selhub J., Folate, vitamin B12 and vitamin B6
安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 70 mg/kg SEX/DURATION : female 7-13 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 7,1132,1973
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 70 mg/kg SEX/DURATION : female 8-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - physical REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 7,1132,1973