Beclomethasone 倍氯米松溶液
CAS 4419-39-0 MFCD00135614
化学结构图
SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
化学属性
| Mol. Formula | C22H29ClO5 |
|---|---|
| Mol. Weight | 408.92 |
| Melting Point | 198 |
| Stability | 对光敏感 |
别名和识别编码
| Chemical Name | Beclomethasone |
|---|---|
| CAS Number | 4419-39-0 |
| Synonym | (11,16)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (11?,16?)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-Chloro-11beta,17,21-trihydroxy-16beta-methyl-pregna-1,4-diene-3,20-dione 9?-Chloro-16?-methylprednisolone 9ALPHA-CHLORO-16BETA-METHYL-1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpr 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione BECLOMETHASONE Beclometasone Beclomethasone (base and/or unspecified salts) Beclomethasone Dipropionate 5534-09-8 /Base {} { |
| MDL Number | MFCD00135614 |
| PubChem Substance ID | 20469 |
| EC Number | 224-585-9 |
| Chemical Name Translation | 倍氯米松溶液 |
| Merck Number | 13,1020 |
| LabNetwork Molecule ID | LN00194291 |
| InChI | InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Cell Signaling and Neuroscience, GlaxoSmithKline, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, B, GlaxoSmithKline, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, GlaxoSmithKline, Immune Cell Signal
产品应用
- 校准仪器和装置；评价方法；工作标准；质量保证/质量控制
相关文献及参考
- Brogden, R.N., et al.: Drugs, 28, 99 (1984),
- Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982),
- Rao, M., et al.: J. Asthma, 19, 21 (1982),
- Small, P., et al.: Ann. Allergy, 49, 127 (1982),
- [1]. He S, et al. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45.
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
其他信息
- 方法一:由地塞米松制得。
- 用途一:制取倍氯米松二丙酸酯。
- Sigma Aldrich:4419-39-0(sigmaaldrich)
- MOL 文件:4419-39-0.mol
- 上游原料:地塞米松
