Naringin 柚皮苷
CAS 10236-47-2 MFCD00148888
化学结构图
SMILES: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC3C=C(O)C4C(=O)C[C@H](OC=4C=3)C3C=CC(O)=CC=3)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
化学属性
| Mol. Formula | C27H32O14 |
|---|---|
| Mol. Weight | 581 |
| Melting Point | 166 ºC |
| TSCA | Yes |
| Density | 1.66 |
别名和识别编码
| Chemical Name | Naringin |
|---|---|
| Synonym | Naringenine-7-rhamnosidoglucoside 柚皮甙 |
| MDL Number | MFCD00148888 |
| PubChem Substance ID | 87573467 |
| Beilstein Registry Number | 102012 |
| EC Number | 233-566-4 |
| CAS Number | 10236-47-2 |
| Merck Number | 6425 |
| Chemical Name Translation | 柚皮苷 |
| Reaxys-RN | 102012 |
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Carbohydrates A to Z, Carbohydrates M-O, Citrus aurantium (Seville orange), Flavonoids, Flavonols, and Flavanols, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), 生化试剂, 碳水化合物, 细胞生物学,
- {SNA} Carbohydrates A to Z, Carbohydrates M-O, Citrus aurantium (Seville orange), Flavonoids, Flavonols, and Flavanols, Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), 生化试剂, 碳水化合物, 细胞生物学, 营养研究
- {SNA} Natural Dyes, Stains and Dyes, 细胞生物学, 血液学和组织学
- {SNA} Citrus aurantium (Seville orange), Flavonoids, Flavonols, and Fl
产品应用
- 苦味剂。本品经水解加氢所得柚苷二氢查耳酮为甜味剂，甜度约为蔗糖的150倍。
相关文献及参考
- [2]. Raha S, et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. Int J Oncol. 2015 Sep;47(3):1061-9.
- [3]. Kulasekaran G, et al. Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. Mol Cell Biochem. 2015 Nov;409(1-2):199-211.
- [4]. Wang D, et al. Naringin Improves Neuronal Insulin Signaling, Brain Mitochondrial Function, and Cognitive Function in High-Fat Diet-Induced Obese Mice. Cell Mol Neurobiol. 2015 Oct;35(7):1061-71.
- Merck:14,6424
- Merck:14,6424 Beilstein:18,528
- [1]. Chen F, et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative
- [1]. Chen F, et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. PLoS One. 2015 Nov 30;10(11):e0143868.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S22 Do not breathe dust 不要吸入粉尘；
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S37 Wear suitable gloves 戴适当手套；
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 19,207,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EKMMA8 Eksperimentalna Meditsina i Morfologiya. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1962- Volume(issue)/page/year: 19,207,1980
