Piperazine Hexahydrate 哌嗪六水合物
CAS 142-63-2 MFCD00149389
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分类
- {SNA} Analytical Standards, Antibiotics Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
- {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards P - R,
- {SNA} Analytical Standards,
- {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; 7fragments
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, P, PER - POLA, 分析/色谱
- {SNA} Analytical Standards, Chromatography, EP Standards, EP Standards P - R, Pharmaceutical Standards, Pharmacopeia Standards, 分析/色谱
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, P, PER - POLA
产品应用
- 用于医药、造船及塑料工业。
相关文献及参考
- Merck: 14,7464 Beilstein:23,4
- Merck: 14,7464
- Short: III/5a
- Short: EINECS
安全信息
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P303+P361+P353+P310+P363
- P304+P340
- P305+P351+P338
- P305+P351+P338+P310
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S22 Do not breathe dust 不要吸入粉尘;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R34 Causes burns 会导致灼伤
- R42/43
- R52/53
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 11200 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,336,1963
其他信息
- 上游原料:乙醇胺 --> 二乙醇胺
- Alfa Aesar:哌嗪六水合物,98+% Piperazine hexahydrate, 98%(142-63-2)
- 外观性质:白色或浅黄结晶,溶于水和酸。熔点:41-45℃沸点145-156℃闪点:87℃
- Sigma Aldrich:142-63-2(sigmaaldrich)
- 蒸气压:0.8 mm Hg ( 20 °C)
- TCI Shanghai:哌嗪六水合物 Piperazine Hexahydrate,>;97.0%(T)(142-63-2)
- 图谱信息:哌嗪(六水) (142-63-2)红外图谱(IR1) 哌嗪(六水) (142-63-2)核磁图( 1 HNMR) 哌嗪(六水) (142-63-2)红外图谱(IR3) 哌嗪(六水) (142-63-2)红外图谱(IR2) 哌嗪(六水) (142-63-2)核磁图( 13 CNMR) 哌嗪(六水) (142-63-2)质谱(MS)
- 下游产品:哌嗪 --> 乙二胺 --> N-甲基哌嗪 --> 三乙烯二胺 --> 1-乙酰哌嗪 --> 1-[(3-吡啶)甲基]哌嗪 --> 1-乙酰基-4-(4-羟基苯基)哌嗪 --> 1-氨基-4-甲基哌嗪 --> 4-甲基-1-甲酰基哌嗪 --> 对甲氧基苯乙酸 --> 1-(2-羟乙基)哌嗪 --> 2-[2-(1-哌嗪基)乙氧基]乙醇 --> 哌嗪柠檬酸盐水合物 --> 1-二乙氨基甲酰基哌嗪 --> 7-氯-4-(1-哌嗪基)喹啉
- Acros Organics:哌嗪六水合物/双二甲胺 Piperazine hexahydrate, 98%(142-63-2)
- {Chemicalbook