Sodium (4R)-N-(2-sulfoethyl)-4-((3R,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanimidate hydrate (4R)-N-(2-磺乙基)-4-((3R,7R,10S,12S,13R,17R)-3,7,12-三羟基-10,13-二甲基十六氢-1H-环戊[a]菲-17-基)戊二酸钠水合物

CAS 345909-26-4 MFCD00150819

化学结构图

345909-26-4
SMILES: O.[Na+].C[C@@H](CCC(=O)NCCS([O-])(=O)=O)[C@@H]1CC[C@@H]2[C@@H]3[C@@H](C[C@@H](O)[C@]21C)[C@]1(C)CC[C@H](O)C[C@@H]1C[C@@H]3O |&1:3,15,18,19,20,22,24,26,30,33,35|

化学属性

Mol. FormulaC26H44NNaO7S
Mol. Weight538
TSCAYes
Melting Point230

别名和识别编码

Chemical NameSodium (4R)-N-(2-sulfoethyl)-4-((3R,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanimidate hydrate
CAS Number345909-26-4
Synonym 牛磺胆酸钠 牛胆酸钠 水合物 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide 牛磺胆酸 钠盐 牛胆酸钠盐 Taurocholic acid sodium salt 牛磺胆酸 钠盐 水合物 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid 2-[[(3?,5?,7?,12?)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid 牛胆酸钠 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide 牛胆酸钠 水合物
MDL NumberMFCD00150819
Beilstein Registry Number3901620
EC Number205-653-7
PubChem Substance ID24278230
Merck Number9075
Chemical Name Translation(4R)-N-(2-磺乙基)-4-((3R,7R,10S,12S,13R,17R)-3,7,12-三羟基-10,13-二甲基十六氢-1H-环戊[a]菲-17-基)戊二酸钠水合物
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分类

  • {SA} Anionic Detergents, Bile Acid Metabolism, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, D to K, Detergents, Detergents N to Z, Detergents by Applications, Drug Efflux Pumps, Electrophoresis Chromatography, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Glutathione S-transferase, Lipids, Membrane Protein Solubilization, Metabolic Pathways, Metabolomics, Multi-Drug Resistance, Multi-D
  • {SNA} Anionic Detergents,
  • {SNA} Anionic Detergents,

产品应用

  • 脂酶加速剂。阴离子去除剂,用于蛋白质的溶解。制备细菌培养基(肠道细菌培养与分离)。用于溶解非结合性胆红素

相关文献及参考

  • Mills, K.A., et al.: Pedatric Res., 43, 3 (1998).
  • [1]. Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5(5):511-22.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
RTECSKI8019250

其他信息

  • 先甜而后苦。有吸湿性。易溶于水和乙醇,不溶于乙醚。有刺激性。水中溶解度: > 250 g/L (20°C)

系列性分类


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