Calcium ionophore III 钙离子载体 A23187, 来源于链霉菌属
CAS 52665-69-7 MFCD00151202
化学结构图
SMILES: CNC1C=CC2OC(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC=2C=1C(O)=O
化学属性
| Mol. Formula | C29H37N3O6 |
|---|---|
| Mol. Weight | 523.62 |
| Melting Point | 182-193 |
别名和识别编码
| Chemical Name | Calcium Ionophore A23187 |
|---|---|
| Synonym | 钙离子载体 III |
| CAS Number | 52665-69-7 |
| PubChem Substance ID | 24277964 |
| EC Number | 258-084-1 |
| Beilstein Registry Number | 1096801 |
| MDL Number | MFCD00151202 |
| Chemical Name Translation | 钙离子载体 A23187, 来源于链霉菌属 |
| Wiswesser Line Notation | T56 BN DOJ HM1 IVQ C1- FT6OXTJ E1 B-& BT6OXTJ C1 E1FY1&V- BT5MJ |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} A - K, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Interferes with Cell Membrane Permeability (Ionophores),
- {SNA} A - K, Antibacterial, Antibiotics A to Z, Antibiotics A-F, Calcium Ionophores, Calcium Signaling Research Tools, Chemical Activators and Inhibitors of ER Stress, Endoplasmic Reticulum Stress, Interferes with Cell Membrane Permeability (Ionophores), Intracellular Calcium Signaling, Mechanism of Action, Spectrum of Activity, 抗生素, 生化试剂, 细胞信号转导和神经科学, 细胞生物学
- A - K, Antibacterial, A
相关文献及参考
- Yamada, P., et al., Inhibitory effect of various Tunisian olive oils on chemical mediator release and cytokine production by basophilic cells. J. Neurophysiol. 116 , 279-87, (2008) 摘要
- Bode, G., et al., Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9. J. Bacteriol. 283 , 31776-84, (2008) 摘要
- Wani, N.A., Chemical activation of in vitro matured dromedary camel (Camelus dromedarius) oocytes: optimization of protocols. Ther. Drug Monit. 69 , 591-602, (2008)
- Henry, M.L., et al., Whole blood aggregation and coagulation in db/db and ob/ob mouse models of type 2 diabetes. Blood Coag. Fibrinolysis 19 , 124-34, (2008) 摘要
- Heaslip, A.T., et al., TgICMAP1 is a novel microtubule binding protein in Toxoplasma gondii. PLoS Biol. 4 , e7406, (2009) 摘要
- Wohlmuth, H., et al., Diarylheptanoid From Pleuranthodium Racemigerum With In Vitro Prostaglandin E(2) Inhibitory And Cytotoxic Activity. J. Nat. Prod. 73 , 743-6, (2010) 摘要
- Khatir, H., et al., In Vitro And In Vivo Developmental Competence Of Dromedary (Camelus Dromedarius) Oocytes Following In Vitro Fertilization Or Parthenogenetic Activation. Anim. Reprod. Sci. 113 , 212-9, (2009) 摘要
- Kayama, H., et al., NFATc1 Mediates Toll-like Receptor-independent Innate Immune Responses During Trypanosoma Cruzi Infection. PLoS Pathog. 5 , e1000514, (2009) 摘要
- Heaslip, A.T., et al., TgICMAP1 Is A Novel Microtubule Binding Protein In Toxoplasma Gondii. PLoS ONE 4 , e7406, (2009) 摘要
- MrówczyÅ„ska, L., et al., Echinophilic Proteins Stomatin, Sorcin, And Synexin Locate Outside GangliosideM1 (GM1) Patches In The Erythrocyte Membrane. Biochem. Biophys. Res. Commun. 401 , 396-400, (2010) 摘要
- Pressman, B.C., et al.
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcu
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9200 ug/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea REFERENCE : NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 9,99,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 469,281,1977
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 8,123,1988
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : >13 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 8,123,1988
TYPE OF TEST : LD50 - Lethal d
