CAS 70563-58-5 MFCD00151702-Geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-,(15R)- TAO{mole}

Geldanamycin, 17-demethoxy-15-methoxy-11-O-methyl-,(15R)-

CAS 70563-58-5 MFCD00151702

化学结构图

SMILES: C[C@H]1C=C(C)[C@H](OC(N)=O)[C@H](C=CC=C(C)C(=O)NC2=CC(=O)C=C([C@H](OC)[C@@H](C)C[C@H](OC)[C@@H]1OC)C2=O)OC |c:2,11,13|

化学属性

Mol. Formula	C30H42N2O9
Mol. Weight	574.66

别名和识别编码

Chemical Name	Herbimycin A from Streptomyces hygroscopicus
MDL Number	MFCD00151702
PubChem Substance ID	24895756
Beilstein Registry Number	4834067
Synonym	Antibiotic Tan 420F Herbimycin A from Streptomyces hygroscopicus Herbimycin A
CAS Number	70563-58-5

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分类

{SNA} Anti
{SNA} Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Antiviral, Benzenoids, Bioactive Small Molecule Alphabetical Index, Chemical Structure Class, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, H, Inhibits an Enzyme, Kinase/Phosphatase Biology, Mechanism of Action, P to Q, Protein Kinase Inhibitors, Protein kinase, tyrosine, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Spectrum of Activity, Tyrosine Kinase (TK), 抗生素, 生化试剂, 生物活性小分子,

安全信息

RTECSLX8930000

WGK Germany3

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,1114,1980