Capsazepine 辣椒平
CAS 138977-28-3 MFCD00153778
化学结构图
SMILES: Oc1cc2c(cc1O)CN(C(=S)NCCc1ccc(Cl)cc1)CCC2
化学属性
| Mol. Formula | C19H21ClN2O2S |
|---|---|
| Mol. Weight | 377 |
| TSCA | No |
| Melting Point | 159-161° |
别名和识别编码
| Chemical Name | Capsazepine |
|---|---|
| CAS Number | 138977-28-3 |
| Synonym | Capsazepine N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide capsazepine |
| MDL Number | MFCD00153778 |
| PubChem Substance ID | 2733484 |
| Chemical Name Translation | 辣椒平 |
| LabNetwork Molecule ID | LN01262800 |
| InChI | InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) |
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分类
- {SNA} Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals, Vanilloids
- Inhibitors
- {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Neurobiology, Neuroscience, Pharmacologicals, Vanilloids, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Amines
- Aromatics
产品应用
- A selective vanilloid receptor antagonist (Ki=3.2uM)
相关文献及参考
- Dickenson and Dray: Br. J. Pharmacol., 104, 1045 (1991),
- Kwak, et al.: Neuroscience, 86, 619 (1998),
