TBPS
CAS 70636-86-1 MFCD00168049
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Antagonists, B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chloride Channel Modulators, GABA and Glycine Receptor Modulators, GABAergics, Ion Channels, Ligand-Gated Ion Channels, Monovalent Ion Channels, Neuroscience,
相关文献及参考
- Behrends, J.C., Modulation by bicuculline and penicillin of the block by t-butyl-bicyclo-phosphorothionate (TBPS) of GABA(A)-receptor mediated Cl − -current responses in rat striatal neurones. Br. J. Pharmacol. 129 , 402, (2000) 摘要
- Jursky, F., et al., Identification of amino acid residues of GABA(A) receptor subunits contributing to the formation and affinity of the tert-butylbicyclophosphorothionate binding site. J. Neurochem. 74 , 1310-1316, (2000) 摘要
- Poulter, M.O., Evidence that GABA A receptor subunit mRNA expression during development is regulated by GABA A receptor stimulation. J. Neurochem. 68 , 631, (1997) 摘要
- Tehrani, M.H, et al., Interaction of t-butylbicyclo-phosphorothionate with γ-aminobutyric acid-gated chloride channels in cultured cerebral neurons. J. Neurochem. 46 , 1542-1548, (1986) 摘要
- Casida, et al., Bicycloorthocarboxylate convulsants. Potent GABA-A receptor antagonists. Mol. Pharmacol. 28 , 246, (1985) 摘要
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 53 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,287,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 55 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 38,1734,1990