4-(4-Nitro-Phenyl)-Thiazol-2-Ylamine 4-(4-硝基苯基)-1,3-噻唑-2-胺

CAS 2104-09-8 MFCD00170222

化学结构图

2104-09-8
SMILES: Nc1nc(-c2ccc([N+](=O)[O-])cc2)cs1

化学属性

Mol. FormulaC9H7N3O2S
Mol. Weight221.24
Melting Point283-287 °C

别名和识别编码

Chemical Name4-(4-Nitro-Phenyl)-Thiazol-2-Ylamine
CAS Number2104-09-8
Alfabeta NameNITROPHENYLTHIAZOLAMINE 44132()------,
MDL NumberMFCD00170222
PubChem Substance ID16420
Synonym 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-1,3-thiazol-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-(4-Nitrophenyl)-
Chemical Name Translation4-(4-硝基苯基)-1,3-噻唑-2-胺
InChIKeyRIKJWJIWXCUKQV-UHFFFAOYSA-N
Wiswesser Line NotationT5N CSJ BZ ER DNW
Beilstein Registry Number0200321
LabNetwork Molecule IDLN00133850
InChIInChI=1S/C9H7N3O2S/c10-9-11-8(5-15-9)6-1-3-7(4-2-6)12(13)14/h1-5H,(H2,10,11)
Canonical SMILESNC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=CS1
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分类

  • {SNA} Building Blocks, C8 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Thiazoles

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSXJ2860000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xn Xn,Xi Xi
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9600 mg/kg/46W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - leukemia
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   33,1593,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2150 mg/kg/13W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   54,841,1975

Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitr

其他信息

  • 储运特性:库房通风低温干燥
  • 刺激数据:眼睛-兔子 500 毫克/24小时轻度
  • 灭火剂:干粉、泡沫、砂土, 二氧化碳, 雾状水
  • 毒性分级:低毒
  • Sigma Aldrich:2104-09-8(sigmaaldrich)
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物和硫氧化物烟雾
  • MOL 文件:2104-09-8.mol
  • 急性毒性:口服-大鼠 LD50: 14200 毫克/公斤
  • 类别:有毒物品

系列性分类


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