CAS 55-63-0 MFCD00171649-Nitroglycerin [USP:JAN] 硝化甘油 TAO{mole}

Nitroglycerin [USP:JAN] 硝化甘油

CAS 55-63-0 MFCD00171649

化学结构图

SMILES: [O-][N+](=O)OC(CO[N+]([O-])=O)CO[N+]([O-])=O

化学属性

Mol. Formula	C3H5N3O9
Mol. Weight	227.11
Flash Point	12°C
Solubility	不溶于水。

别名和识别编码

Chemical Name	Nitroglycerin [USP:JAN]
Synonym	{uni_hamburg} Nysconitrine Myoglycer { Nitroglycerol Glycerol trinitrate (componentof)sdmno37 Nitrostat Blasting oil Nitrogliceryna Glycerintrinitrat 丙三醇三硝酸酯 Klavikordal Solution glyceryl trinitrate Angised 1,2,3-tris-nitryloxy-propane 三硝酸甘油 Angorin NK 843 Nitrol (pharmaceutical) Aquo-trinitrosan 1,2,3-tris-(nitryloxy)-propane glycerol trinitrate Nitroling NITROGLYCERIN Nitroletten Angiolingual Nitora Nitroglycerine Nitrolowe Angibid Spirit of glyceryl trinitrate Nitroretard GTN Myocon {uni Nitrozel 1,2,3 Nitrostabilin Nitromel Nitronet 1,2,3-Propanetriyl Nitrate Nitro-lent Niong {uni_ha Glyceryl trinitrate {hazar {uni_ Glycerintrinitrate {un GLYCEROL TRINITRATE Lenitr {haz 永保心灵 Glyceroltrinitrat Trinitrin Nitro-Span 三硝[基]甘油 Myoglycerin {uni_h RCRA waste number P081 硝酸甘油 Gilucor nitro Chitamite Vasoglyn Nitroglycerin Blasting gelatin S.N.G TNG Nitro-span {ha Glyceryl nitrate TRINITROGLYCERIN NG {Chemicalboo Nitrine Niglin 三硝酸丙三醇 Glycerol(trinitrate de) {hazard_
EC Number	200-240-8
CAS Number	55-63-0
MDL Number	MFCD00171649
Chemical Name Translation	硝化甘油
Wiswesser Line Notation	WNO1YONW1ONW
Beilstein Registry Number	1802063
InChIKey	SNIOPGDIGTZGOP-UHFFFAOYSA-N

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

UN Number 0143/0144/1204/3064 1993

Packing GroupI

Hazard Codes E,T+,N

Hazard Class1.1A

Safety Statements

S35 This material and its container must be disposed of in a safe way 该物料及其容器必须以安全方式处置；
S7 Keep container tightly closed 保存在严格密闭容器中；
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S33 Take precautionary measures against static discharges 对静电采取预防措施；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
R3 Extreme risk of explosion by shock, friction, fire or other sources of ignition 遇到震动、摩擦、火焰或者其它引燃物有极端爆炸危险
R33 Danger of cumulative effects 有累积作用的危险
R51/53
R11 Highly flammable 非常易燃

Warnings 危化品目录(2015) 危险化学品

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 438 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - testicular tumors
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 4,88,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 36500 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 4,88,1980

RTECSQX2100000

TYPE OF TEST            : LDLo - Lowest publi

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,547,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 8 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AEMED3 Annals of Emergency Medicine.  (American College of Emergency
   Physicians, 1125 Executive Circle, Irving, TX 75038)
   Volume(issue)/page/year: 23,31,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1607 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,786,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Ro

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2500 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,187,1993

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/well
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   19,77,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3640 mg/kg
SEX/DURATION            : female 17-21 day(s) after conception
                          lactating female 21 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 18,3564,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 11 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2580 mg/kg
SEX/DURATION            : male 91 day(s) pre-mating
                          female 2 week(s) pre-mating  - 7 day(s) after
                          conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Effects on Embryo or Fetus - other effects to e

其他信息

外观性质:淡黄色稠厚液体，低温易冻结。
急性毒性:口服-大鼠 LD50: 7060 毫克/公斤; 口服-小鼠 LD50: 3450 毫克/公斤
毒性分级:中毒
灭火剂:水
储运特性:轻装轻放; 库房通风、远离明火、高温、阳光; 与氧化剂、易燃物, 食品原料分开存放
刺激数据:皮肤-兔子 20毫克/24小时中度; 眼睛-兔子 500 毫克/24小时轻度
Sigma Aldrich:55-63-0(sigmaaldrich)
类别:易燃液体
MSDS 信息:硝化甘油(55-63-0).msds
爆炸物危险特性:与空气混合形成爆炸性混合物
可燃性危险特性:易燃; 含有毒硝化甘油
职业标准:TWA 0.5 毫克/ 立方米; STEL 1 毫克/ 立方米
MOL 文件:55-63-0.mol