Pholedrine 对羟基甲基苯丙胺
CAS 370-14-9 MFCD00178702
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            分类
- Aromatics
 - Pharmaceuticals
 - Intermediates & Fine Chemicals
 - {SNA} Alphabetic, Amphetamine, Analytical Standards, Analytical/Chromatography, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, H, HU - HZ, Neat Compounds
 
相关文献及参考
- Glennon, R., et al.: J. Med. Chem., 23, 294 (1980),
 - de Letter, E., et al.: J. Anal. Toxicol., 26, 113 (2002),
 - Lin, D., et al.: J. Anal. Toxicol., 31, 109 (2007),
 
安全信息
 GHS Symbol
 
        
            
            
 - P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
 - P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
 - P264+P265
 - P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
 - P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
 - P302+P352
 - P304+P340
 - P305+P351+P338
 - P319
 - P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
 - P332+P317
 - P337+P317
 - P362+P364
 - P403+P233
 - P405 Store locked up. 上锁保管。
 - P501 Dispose of contents/container to..… 处理内容物/容器.....
 
- H315 Causes skin irritation 会刺激皮肤
 - H319 Causes serious eye irritation 严重刺激眼睛
 - H335 May cause respiratory irritation 可能导致呼吸道刺激
 
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
 - S36 Wear suitable protective clothing 穿戴适当的防护服;
 
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
 
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 119 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,328,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Behavioral - changes in psychophysiological tests REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 159,442,1966
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,101,1948TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940
