1-Hydroxy-7-azabenzotriazole, 98% N-羟基-7-氮杂苯并三氮唑(HOAT)

CAS 39968-33-7 MFCD00210053

化学结构图

39968-33-7
SMILES: ON1N=NC2C=CC=NC1=2

化学属性

Mol. FormulaC5H4N4O
Mol. Weight136
Melting Point213-216°C
Refractive indexn20/D 1.441
Density0.973 g/mL at 20 °C
Flash Point213-216°C

别名和识别编码

Chemical Name1-Hydroxy-7-azabenzotriazole, 98%
CAS Number39968-33-7
Alfabeta NameTRIAZOLOPYRIDINOL HB3123453[[]]----,,,
MDL NumberMFCD00210053
Synonym 1-HYDROXY-7-AZABENZOTRIAZOL 1-HYDROXY-7-AZABENZOTRIAZOLE 0.5 TO & 1-HYDROXY-7-AZABENZOTRIAZOLE SOLUTION, 0.5M IN DMF 1-Hydroxy-7-azabenotriazole 1-Hydroxy-7-azabenzotriazole (HOAt) 1-羟基-7-偶氮苯并三氮唑 1-羟基-7-偶氮苯并三氮唑(HOAt) 1-羟基-7-叠氮苯并三唑 1-羟基-7-氮杂苯并三唑 1H-[1,2,3]triazolo[4,5-b]pyridine 3-Oxide 3H-1 3H-1,2,3-TRIAZOLO[4,5-B]PYRIDINE, 3-HYDROXY- 3H-1,2,3-Triazolo[4,5-b]pyridin-3-ol, 7-Aza-1-hydroxybenzotriazole 3H-[1,2,3]-TRIAZOLO[4,5-B]PYRIDIN-3-OL 3H-[1,2,3]-Triazolo[4,5-b]pyridin-3-ol HOAt 3H-[1,2,3]-三唑[4,5-b]吡啶-3-醇 HOAt 7-AZA-1-HYDROXYBENZOTRIAZOLE CHEM-1893 HO-EPCP HOAT HOAT [1-HYDROXY-7-AZABENZOTRIAZOLE] N-羟基-7-偶氮苯并三氮唑 N-羟基-7-偶氮苯并三氮唑 溶液
Beilstein Registry Number1211115
PubChem Substance ID57650093
EC Number250-023-7
Reaxys-RN1211115
Chemical Name TranslationN-羟基-7-氮杂苯并三氮唑(HOAT)
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分类

  • Bases & Related Reagents
  • {SNA} Active Esters/Additives, Chemical Synthesis, Coupling, Others, Synthetic Reagents
  • Heterocycles
  • Nucleotides
  • {SNA} Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling, Synthetic Reagents

产品应用

  • 多肽缩合中抑制消旋的产生,也用于片断缩合。

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P370+P380
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H318 Causes serious eye damage 严重伤害眼睛
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H228 Flammable solid 易燃固体
  • H315 Causes skin irritation 会刺激皮肤
  • H204 Fire or projection hazard 火灾或喷射危险。
  • H301 Toxic if swallowed 吞食有毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302+H312+H332
Signal word Danger Warning
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S15 Keep away from heat 远离热源;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Packing GroupII
UN Number 0481 1325
Hazard Codes 4.1 T T,Xi,F,Xn,E
Storage condition Store at RT. 阴凉干燥处保存。
Hazard Class1.4S

其他信息

  • 外观性质:白色或灰白色粉末。熔点:213~216℃闪点:58 °C折光率:1.4390
  • N-羟基-7-氮杂苯并三氮唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw020059 1-羟基-7-氮杂苯并三氮唑 (HOAt)(2-8℃) 5g 180元 2011/04/16 T1673 3H-1,2,3-三唑并[4,5-b]吡啶-3-醇[肽偶联添加剂] 3H-1,2,3-Triazolo[4,5-b]pyridin-3-ol [Peptide Coupling Additive] 5G 1599元 2011/04/16 T1673 3H-1,2,3-三唑并[4,5-b]吡啶-3-醇[肽偶联添加剂] 3H-1,2,3-Triazolo[4,5-b]pyridin-3-ol [Peptide Coupling Additive] 25G 5399元
  • TCI Shanghai:1-羟基-7-氮杂苯并三唑[肽偶联添加剂] 3H-1,2,3-Triazolo[4,5-b]pyridin-3-ol [Peptide Coupling Additive],>;98.0%(LC)(T)(39968-33-7)
  • 检测方法:HPLC
  • 下游产品:2-乙基哌嗪
  • Sigma Aldrich:39968-33-7(sigmaaldrich)
  • Hazard Note:Irritant
  • Decomposition:213-216 °C
  • 用途一:多肽缩合中抑制消旋的产生,也用于片断缩合。
  • 图谱信息:N-羟基-7-氮杂苯并三氮唑(39968-33-7)质谱(MS) N-羟基-7-氮杂苯并三氮唑(39968-33-7)核磁图( 1 HNMR) N-羟基-7-氮杂苯并三氮唑(39968-33-7)红外图谱(IR2) N-羟基-7-氮杂苯并三氮唑(39968-33-7)核磁图( 13 CNMR) N-羟基-7-氮杂苯并三氮唑(39968-33-7)红外图谱(IR1)
  • MOL 文件:39968-33-7.mol

系列性分类


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